Simple Summary Colorectal cancer is one of the leading causes of cancer-associated
deaths worldwide. From the 1960s to 2002, the standard systemic treatment consisted of …

Simple Summary Tumors in the pancreas and colon are still too often an unmet clinical
problem. Cells from these cancers and normal cells have different gene expression profiles …

Background BRAF mutation occurs in 5%–10% of metastatic colorectal cancers (mCRCs).
Patients with BRAF mutant mCRC exhibit a specific metastatic pattern and poor prognosis …

Background: Rectal cancers, or rectal neoplasms, are tumors that develop from the lining of
the rectum, the concluding part of the large intestine ending at the anus. These tumors often …

Background and Objectives: We aimed to investigate the role of Wnt2 expression in
colorectal cancer (CRC) prognosis and evaluate its potential as a therapeutic target in BRAF …

Although surgical resection could provide better survival for patients with colorectal cancer
liver metastases (CRLM), the recurrence rate after resection of CRLM remains high. The …

The progress made in Next-Generation Sequencing technology has resulted in many
genetic databases, which offer the potential for more effective diagnostic tools. Recent …

BRAF non-V600 mutations are a distinct molecular subset of colorectal cancer (CRC) that
has little to no clinical similarity to the BRAF V600 mutations. It is generally considered that …