Abstract Chitinase‐3‐like protein 1 (CHI3L1) is a secreted glycoprotein characterized by its
ability to regulate multiple biological processes, such as the inflammatory response and …

Several reports have pointed out that Chitinases are expressed and secreted by various cell
types of central nervous system (CNS), including activated microglia and astrocytes. These …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by
progressive motor neuron damage. Due to the complexity of the ALS, so far the etiology and …

Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is an inflammatory neurodegenerative disease that affects motor …

The choroid plexus (ChP) produces and is bathed in the cerebrospinal fluid (CSF), which in
aging and Alzheimer's disease (AD) shows extensive proteomic alterations including …

Neurological disorders are the leading cause of cognitive and physical disability worldwide,
affecting 15% of the global population. Due to the demographics of aging, the prevalence of …

Chitinase-3-like protein-1 (CHI3L1), also known as YKL40, is a glycoprotein that belongs to
the chitinase protein family. It is involved in various biological functions, including cell …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a multifactorial neurodegenerative disorder
with a significant contribution of non-cell autonomous mechanisms to motor neuronal …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the degeneration of motor neurons, and there is currently a lack of reliable diagnostic …

Leukodystrophies represent a large and complex group of inherited disorders affecting the
white matter of the central nervous system. Adult-onset leukoencephalopathy with axonal …