Advancing immunosuppression in liver transplantation: A narrative review

S Iesari, FL Nava, IE Zais, L Coubeau… - … & Pancreatic Diseases …, 2024 - Elsevier
Immunosuppression is essential to ensure recipient and graft survivals after liver
transplantation (LT). However, our understanding and management of the immune system …

[HTML][HTML] Advances in the understanding and exploitation of carbohydrate-active enzymes

RK Bains, SA Nasseri, JF Wardman… - Current Opinion in …, 2024 - Elsevier
Carbohydrate-active enzymes (CAZymes) are responsible for the biosynthesis, modification
and degradation of all glycans in Nature. Advances in genomic and metagenomic …

Enzymatic conversion of human blood group A kidneys to universal blood group O

S MacMillan, SA Hosgood, L Walker-Panse… - Nature …, 2024 - nature.com
ABO blood group compatibility restrictions present the first barrier to donor-recipient
matching in kidney transplantation. Here, we present the use of two enzymes, Fp GalNAc …

Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood

M Jensen, L Stenfelt, J Ricci Hagman, MJ Pichler… - Nature …, 2024 - nature.com
Matching donor and recipient blood groups based on red blood cell (RBC) surface ABO
glycans and antibodies in plasma is crucial to avoid potentially fatal reactions during …

Glycoengineering in antigen-specific immunotherapies

Y Li, H Chen, J Gao, P Wu, S Hong - Current Opinion in Chemical Biology, 2024 - Elsevier
Advances in immunotherapy have revolutionized modern medical care paradigms.
However, many patients respond poorly to the current FDA-approved treatment regimens …

Current evidence and future perspectives to implement continuous and end-ischemic use of normothermic and oxygenated hypothermic machine perfusion in clinical …

M Foguenne, S MacMillan, P Kron, J Nath… - Journal of clinical …, 2023 - mdpi.com
The use of high-risk renal grafts for transplantation requires the optimization of pretransplant
assessment and preservation reconditioning strategies to decrease the organ discard rate …

Global Health Disparities and Trafficking of Human Beings for the Purpose of Organ Removal

A Manzano - Human Trafficking: A Global Health Emergency …, 2023 - Springer
There are many complex reasons why people sell and buy human organs and how global
criminal networks benefit from this commercialization. This trade includes people who are …

Organ-quarantined therapy: in situ normothermic machine perfusion of the renal allograft in a patient with a kidney transplant and an abdominal aortic aneurysm

J Qiu, M Wang, S Yu, G Wu, W Wu… - British Journal of …, 2023 - academic.oup.com
To prevent kidney ischemia injury from common iliac artery blockage during surgical
resection of AAA, we developed an in situ closed NMP system to specifically maintain the …

Gépi perfúzió a vesetranszplantációban

F Tóth, A Szijártó, L Piros - Orvosi Hetilap, 2023 - akjournals.com
A szervtranszplantáció területén évek óta fennálló probléma az egyre növekvő szervigény
mellett az elérhető donorszervek számának stagnálása. Az ellentét feloldására tett kísérletek …