Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

The brain, particularly the hypothalamus, integrates input from factors that stimulate
(orexigenic) and inhibit (anorexigenic) food intake. In fish, the identification of appetite …

Sleep is an essential behavioral state. It is induced by conserved sleep-active neurons that
express GABA. However, little is known about how sleep neuron function is determined and …

Selective serotonin reuptake inhibitors, such as fluoxetine (FLX), are the most commonly
used drugs in the treatment of major depression. However, there is a limited understanding …

Epilepsy is a chronic brain disease that affects approximately 65 million people worldwide.
However, despite the continuous development of antiepileptic drugs, over 30% patients with …

Energy balance plays an important role in the control of reproduction. However, the cellular
and molecular mechanisms connecting the two systems are not well understood especially …

The pharmacological exploitation of the galanin receptors as drug targets for treatment of
epilepsy, depression, and pain has been hampered by the lack of workable compounds for …

Resilience represents an active adaption process in the face of adversity, trauma, tragedy,
threats, or significant sources of stress. Investigations of neurobiological mechanisms of …

Objective: Galanin (GAL) has a role in the regulation of food intake by way of acting on the
central nervous system in rodents. High serum GAL levels have been observed in obese …

Simple Summary Peptidergic systems play an important role in cancer progression. The
galaninergic system (the peptide galanin and its receptors: galanin 1, 2 and 3) is involved in …