ICU-acquired colonization and infection related to multidrug-resistant bacteria in COVID-19 patients: a narrative review

A Gaudet, L Kreitmann, S Nseir - Antibiotics, 2023 - mdpi.com
A large proportion of ICU-acquired infections are related to multidrug-resistant bacteria
(MDR). Infections caused by these bacteria are associated with increased mortality, and …

Impact of multiplex PCR in the therapeutic management of severe bacterial pneumonia

J Dessajan, JF Timsit - Antibiotics, 2024 - mdpi.com
Pneumonia is a common and severe illness that requires prompt and effective management.
Advanced, rapid, and accurate tools are needed to diagnose patients with severe bacterial …

An Observational Study to Develop a Predictive Model for Bacterial Pneumonia Diagnosis in Severe COVID-19 Patients—C19-PNEUMOSCORE

ES Tanzarella, J Vargas, M Menghini… - Journal of Clinical …, 2023 - mdpi.com
In COVID-19 patients, antibiotics overuse is still an issue. A predictive scoring model for the
diagnosis of bacterial pneumonia at intensive care unit (ICU) admission would be a useful …

Interpreting the results of rapid molecular diagnostic tests for carbapenem-resistant Enterobacterales infection: current clinical perspective while waiting for further …

DR Giacobbe, V Di Pilato, A Vena… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Carbapenem-resistant Enterobacterales (CRE) causing severe
infections in humans have represented an important challenge for clinicians worldwide …

[PDF][PDF] Understanding how diagnostics influence antimicrobial decision-making is key to successful clinical trial design

TM Rawson, LSP Moore - Clinical Microbiology and Infection, 2023 - Elsevier
As the landscape of near-patient, rapid, infection-related diagnostics continues to 29 evolve,
a paucity of large, well-designed clinical trials are available. Most studies 30 within this field …

Clinical utility of procalcitonin in implementation of procalcitonin-guided antibiotic stewardship in the South-East Asia and India: evidence and consensus-based …

ALH Kwa, BR Aninda Sidharta, DN Son… - Expert Review of Anti …, 2024 - Taylor & Francis
ABSTRACT Introduction The South-East Asian (SEA) region and India are highly
susceptible to antibiotic resistance, which is caused due to lack of antimicrobial stewardship …

The Evolving Challenge of Appropriate Antibiotics Use in Hospitalized COVID-19 Patients: A Systematic Literature Review

G Granata, S Cicalini - Antibiotics, 2024 - mdpi.com
The issue of bacterial infections in COVID-19 patients has received increasing attention.
Scant data are available on the impact of bacterial superinfection and antibiotic …

Biomarkers in sepsis

J Saxena, S Das, A Kumar, A Sharma, L Sharma… - Clinica Chimica …, 2024 - Elsevier
Sepsis is a life-threatening condition characterized by dysregulated host response to
infection leading to organ dysfunction. Despite advances in understanding its pathology …

Performance and impact of rapid multiplex PCR on diagnosis and treatment of ventilated hospital-acquired pneumonia in patients with extended-spectrum β …

P Bay, V Fihman, PL Woerther, B Peiffer… - Annals of Intensive …, 2024 - Springer
Background Antimicrobial stewardship (AMS) for ventilator-associated pneumonia (VAP) or
ventilated hospital-acquired pneumonia (vHAP) in extended-spectrum β-lactamase …

Performance and Impact on Antibiotic Prescriptions of a Multiplex PCR in a Real-Life Cohort of Critically Ill Patients with Suspected Ventilated Pneumonia: A …

E Chambe, P Bortolotti, R Diesnis, C Laurans… - Antibiotics, 2023 - mdpi.com
Pulmonary multiplex polymerase chain reaction (m-PCR) allows rapid pathogen detection.
We aimed to assess its impact on initial antibiotic prescriptions in ventilated patients with …