Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Many fungal pathogens undergo morphological transformations during host invasion.
However, the significance of this for fungal pathogenesis is not clear. Both yeast and hyphal …

Candida albicans is the primary fungal pathogen of humans. Despite the need for novel
drugs to combat fungal infections [Sobel, JD (2000) Clin Infectious Dis 30: 652], antifungal …

Cellular immunity is the primary host defense against microbial infections. In the healthy
host, opportunistic fungal pathogens are commensal fungi commonly colonizing human …

Candida albicans remains the main etiological agent of candidiasis, as this otherwise
normal commensal of humans is capable of causing active infection in immune-and …

Candida albicans, one of the pathogenic Candida species, causes high mortality rate in
immunocompromised and high-risk surgical patients. In the last decade, only one new class …

Candida species other than Candida albicans now account for up to 50% of deep
candidiasis cases, yet little attention has been paid to the virulence attributes of these fungi …

Candida species are unusual causes of urinary tract infection (UTI) in healthy individuals,
but common in the hospital setting or among patients with predisposing diseases and …

Introduction: Targeting pathogenetic mechanisms, rather than essential processes,
represents a very attractive alternative for the development of new antibiotics. This may be …

The pathogenic fungus, Candida albicans contains homologues of the transcriptional
repressors ScTup1, ScMig1 and ScNrg1 found in budding yeast. In Saccharomyces …