Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

Simple Summary The most common therapies for severe and recurrent gynecological
cancers are hormone therapy and chemotherapy, and responsiveness to therapy is a key …

Simple Summary Estrogens, belonging to a group of steroid compounds, play an important
role in both physiological and disease processes, mainly by interacting with estrogen …

The standard treatment of ovarian cancer (OC) patients, including debulking surgery and
first-line chemotherapy, is unsatisfactory because of recurrent episodes in the majority …

Ovarian cancer is one of the most common cancers in women and the most concerning
issues in gynecological oncology in recent years. It is postulated that many factors may …

Carborane is a carbon-boron molecular cluster that can be viewed as a 3D analog of
benzene. It features special physical and chemical properties, and thus has the potential to …

Ovarian cancer is one of the most common gynecologic cancers that has the highest
mortality rate. Endometrioid ovarian cancer, a distinct subtype of epithelial ovarian cancer, is …

Background Other than for breast cancer, endocrine therapy has not been highly effective for
gynecologic cancers. Endocrine therapy resistance in estrogen receptor positive …

Ovarian granulosa cell tumor (GCT) is a rare, low‐grade malignant tumor that accounts for
70% of the sex cord‐stromal tumors. It has two histopathologic types with different clinical …

Mycotoxins are secondary metabolites of fungi that may affect both human and animal
health. Some of them possess estrogenic activity, due to direct binding to estrogen receptors …