Microglia have been implicated in various neurological and psychiatric disorders in rodent
and human postmortem studies. However, the dynamic actions of microglia in the living …

As the heterogeneity of symptoms is increasingly recognized among long-COVID patients, it
appears highly relevant to study potential pathophysiological differences along the different …

Microglia, the innate immune cells of the brain, are activated by damage or disease. In
mouse models of amyotrophic lateral sclerosis (ALS), microglia shift from neurotrophic to …

Microglia are key players in the central nervous system in health and disease. Much
pioneering research on microglia function has been carried out in vivo with the use of …

Findings from epidemiological studies, biomarker measurements and animal experiments
suggest a role for aberrant immune processes in the pathogenesis of major depressive …

The regulation of microglial cell phenotype is a potential therapeutic intervention in
neurodegenerative disease. Previously, we reported that transforming growth factor-β (TGF …

Myeloid cells of the central nervous system (CNS), which include parenchymal microglia,
macrophages at CNS interfaces and monocytes recruited from the circulation during …

One long standing aspect of microglia biology was never questioned; their involvement in
brain disease. Based on morphological changes (retracted processes and amoeboid shape) …

Microglia and astroglia play critical roles in the development, function, and survival of
neurons in the CNS. However, under inflammatory conditions the role of astrogliosis in the …

Microglia are important cells in the brain that can acquire different morphological and
functional phenotypes dependent on the local situation they encounter. Knowledge on the …