Macrophages, which are key cellular components of the liver, have emerged as essential
players in the maintenance of hepatic homeostasis and in injury and repair processes in …

Effective delivery of therapeutic and diagnostic nanoparticles is dependent on their ability to
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …

Hepatic macrophages play a central role in maintaining homeostasis in the liver, as well as
in the initiation and progression of liver diseases. Hepatic macrophages are mainly derived …

In this fast-food era, people depend on ready-made foods and engage in minimal physical
activities that ultimately change their food habits. Majorities of such foods have harmful …

Highlights This review focuses on the therapeutic mechanisms, targeting strategies of
various nanomaterials in acute liver failure, and recent advances of diverse nanomaterials …

Acute liver failure (ALF) describes a clinical syndrome of rapid hepatocyte injury leading to
liver failure manifested by coagulopathy and encephalopathy in the absence of pre-existing …

Patients with acute liver failure (ALF) have systemic innate immune suppression and
increased susceptibility to infections. Programmed cell death 1 (PD-1) expression by …

Chronic liver injury of different etiologies may result in hepatic fibrosis, a scar formation
process consisting in altered deposition of extracellular matrix. Progression of fibrosis can …

Drinking alcohol, even in moderation, can affect the immune system. Studies have shown
disproportionate effects of alcohol on circulating and tissue-resident myeloid cells …

Myeloid-derived suppressor cells (MDSCs) are cells of myeloid lineage with a potent
immunosuppressive capacity. They are present in cancer patients as well as in patients with …