Autophagy is a quality-control, metabolic, and innate immunity process. Normative
autophagy affects many cell types, including hematopoietic as well as non-hematopoietic …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Alterations of the mycobiota composition associated with Crohn's disease (CD) are
challenging to link to defining elements of pathophysiology, such as poor injury repair. Using …

In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

The identification of patients with coronavirus disease 2019 and high risk of severe disease
is a challenge in routine care. We performed cell phenotypic, serum, and RNA sequencing …

Interferons (IFNs) are among the first vertebrate immune pathways activated upon viral
infection and are crucial for control of viral replication and dissemination, especially at …

Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …

Immunological adaptations in pregnancy allow maternal tolerance of the semi-allogeneic
fetus but also increase maternal susceptibility to infection. At implantation, the endometrial …

The development of antiretroviral drugs (ARVs) was a great milestone in the management of
HIV infection. ARVs suppress viral activity in the host cell, thus minimizing injury to the cells …

An epidemiological association between multiple sclerosis (MS) and inflammatory bowel
disease (IBD) is well established, but whether this reflects a shared genetic aetiology, and …