Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come
P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - ASPET
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …
Liposomal delivery systems: design optimization and current applications
ASA Lila, T Ishida - Biological and pharmaceutical bulletin, 2017 - jstage.jst.go.jp
The liposome, a closed phospholipid bilayered vesicular system, has received considerable
attention as a pharmaceutical carrier of great potential over the past 30 years. The ability of …
attention as a pharmaceutical carrier of great potential over the past 30 years. The ability of …
Ultra‐Small Nano‐Assemblies as Tumor‐Targeted and Renal Clearable Theranostic Agent for Photodynamic Therapy
D Zhang, KX Teng, L Zhao, LY Niu… - Advanced …, 2023 - Wiley Online Library
It is a challenge to design photosensitizers to balance between the tumor‐targeting
enrichment for precise treatment and efficient clearance within a reasonable timescale for …
enrichment for precise treatment and efficient clearance within a reasonable timescale for …
[HTML][HTML] PEGylation in anti-cancer therapy: An overview
Advanced drug delivery systems using poly (ethylene glycol)(PEG) is an important
development in anti-cancer therapy. PEGylation has the ability to enhance the retention time …
development in anti-cancer therapy. PEGylation has the ability to enhance the retention time …
Biocompatibility of engineered nanoparticles for drug delivery
The rapid advancement of nanotechnology has raised the possibility of using engineered
nanoparticles that interact within biological environments for treatment of diseases …
nanoparticles that interact within biological environments for treatment of diseases …
The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage
ASA Lila, H Kiwada, T Ishida - Journal of Controlled Release, 2013 - Elsevier
Despite the clinical introduction of an increasing number of polyethylene glycol (PEG)-
conjugated substances, PEG has been named as the cause of an unexpected immunogenic …
conjugated substances, PEG has been named as the cause of an unexpected immunogenic …
Challenges in development of nanoparticle-based therapeutics
N Desai - The AAPS journal, 2012 - Springer
In recent years, nanotechnology has been increasingly applied to the area of drug
development. Nanoparticle-based therapeutics can confer the ability to overcome biological …
development. Nanoparticle-based therapeutics can confer the ability to overcome biological …
Targeted delivery methods for anticancer drugs
VV Veselov, AE Nosyrev, L Jicsinszky, RN Alyautdin… - Cancers, 2022 - mdpi.com
Simple Summary The current main technological strategies for the delivery of anticancer
drugs are discussed herein. This comprehensive review may help researchers design …
drugs are discussed herein. This comprehensive review may help researchers design …
Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA
S Chen, YYC Tam, PJC Lin, MMH Sung, YK Tam… - Journal of Controlled …, 2016 - Elsevier
Lipid nanoparticles (LNP) can provide a clinically effective method for delivering small
interfering RNA (siRNA) to silence pathological genes in hepatocytes. The gene silencing …
interfering RNA (siRNA) to silence pathological genes in hepatocytes. The gene silencing …
Evolution of nanocarrier drug-delivery systems and recent advancements in covalent organic framework–drug systems
MC Scicluna, L Vella-Zarb - ACS Applied Nano Materials, 2020 - ACS Publications
Nanotechnology has been actively employed in the development of drug-delivery systems
overcoming the limitations of conventional carriers. In nanomedicine, the ultimate goal is to …
overcoming the limitations of conventional carriers. In nanomedicine, the ultimate goal is to …