Homocysteine promotes intestinal fibrosis in rats with trinitrobenzene sulfonic acid-induced colitis

H Ding, HZ Gan, WJ Fan, LY Cao, JM Xu… - Digestive diseases and …, 2015 - Springer
Abstract Background and Aim Previous studies have revealed significantly increased levels
of plasma and mucosal homocysteine (Hcy) in patients with Crohn's disease (CD); however …

内源性硫化氢和胱硫醚-β-合成酶mRNA 在支气管哮喘大鼠中的表达及意义

方丽, 李昌崇, 童夏生, 王华芳, 王招定 - 中华哮喘杂志(电子版), 2009 - cqvip.com
目的观察支气管哮喘(简称哮喘) 大鼠胱硫醚-β-合成酶(eystathionine-β-synthase, CBS) tuRNA
及硫化氢(hydrogensulfide, HzS) 的表达变化, 探讨CBS 与HzS 的相关性 …

硫化氢对人胚肺成纤维细胞缺氧后增殖活力及细胞凋亡的影响

潘际刚, 刘新宇, 周华, 陈丽, 郑煜 - 中国药理学通报, 2010 - cqvip.com
目的探讨内源性及外源性硫化氢(H2S) 对缺氧诱导下人胚肺成纤维细胞增殖效应及凋亡率的
影响. 方法以2% O2-93% N2-5% CO2 体外培养人胚肺成纤维细胞24h, 制备细胞缺氧模型 …

Study on potential differentially expressed genes in idiopathic pulmonary fibrosis by bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2023 - biorxiv.org
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with reduced
quality of life and earlier mortality, but its pathogenesis and key genes are still unclear. In …

内源性气体信号分子和调节肽在特发性肺纤维化发病中的作用

房立平, 唐朝枢, 刘新民 - 国际病理科学与临床杂志, 2009 - cqvip.com
特发性肺纤维化是一种病因不明的慢性进行性肺疾病, 以纤维增殖, 肺实质的破坏及细胞外基质
的沉积为特征, 其发病机制尚不明确. 近几年的研究发现内源性气体信号分子(一氧化氮 …

Simvastatin impairs the induction of pulmonary fibrosis caused by a western style diet: a preliminary study

P Kruzliak, DL Hare, V Zvonicek… - Journal of cellular …, 2015 - Wiley Online Library
The role of an atherogenic diet in causing pulmonary fibrosis has received little attention and
simvastatin has been shown to reduce pulmonary fibrosis in animal models. To determine if …

同型半胱氨酸对实验性结肠炎大鼠肠纤维化的影响及其机制

丁浩, 梅俏, 李颖, 甘惠中, 曹立宇, 许建明 - 中华消化杂志, 2014 - cqvip.com
肠纤维化导致的肠狭窄是CD 的常见并发症, 超过1/3 的CD 患者因肠狭窄接受手术治疗,
术后约70% 的患者再次发生狭窄, 严重影响患者的生活质量. 同型半胱氨酸(homocysteine, Hcy) …

Identification of Key Genes and Underlying Mechanisms in Cystic Fibrosis and its Associated Complications Based on Bioinformatics Analysis of Next Generation …

B Vastrad, C Vastrad - bioRxiv, 2022 - biorxiv.org
Cystic fibrosis (CF) is one of the inherited autosomal recessive disorders with very
complicated pathogenesis. Identifying the molecular signatures and specific biomarkers of …

Homocysteine is Elevated in COPD

T Seemungal, M Rios… - … disease− current concepts …, 2012 - books.google.com
Homocysteine was first described by Butz and du Vigneaud in 1932 (Butz 1932). An
association between elevated homocysteine levels and human disease was first suggested …

硫化氢抗肺纤维化作用机制的研究进展

李梦, 何振华 - 中国现代医药杂志, 2016 - cqvip.com
肺纤维化(Pulmonary Fibrosis, PF) 是肺部疾病中一种以弥漫性间质性改变为主的疾病,
其发病原因可有多种, 主要可引起肺泡, 肺间质, 肺小血管和终末气道的病变 …