Neutrophils are the most abundant white blood cells in circulation, and patients with
congenital neutrophil deficiencies suffer from severe infections that are often fatal …

The discovery of novel small-molecule antibacterial drugs has been stalled for many years.
The purpose of this review is to underscore and illustrate those scientific problems unique to …

Building and maintaining a homeostatic relationship between a host and its colonizing
microbiota entails ongoing complex interactions between the host and the microorganisms …

Bacterial resistance caused by the overuse of antibiotics and the shelter of biofilms has
evolved into a global health crisis, which drives researchers to continuously explore …

Bacteria and fungi can form a range of physical associations that depend on various modes
of molecular communication for their development and functioning. These bacterial-fungal …

Medical device contamination caused by microbial pathogens such as bacteria and fungi
has posed a severe threat to the patients' health in hospitals. Due to the increasing …

Antimicrobial peptides (AMPs) take part in the immune system by mounting a first line of
defense against pathogens. Recurrent structural and functional aspects are observed …

Antimicrobial peptides of multicellular organisms were first characterized in the 1980s by
investigators who felt that known systems of immunity could not explain what they observed …

Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

There is a continuous need for iterative cycles of antibiotic discovery and development to
deal with the selection of resistant pathogens that emerge as therapeutic application of an …