Tridecaptin A1 (TriA1) is a nonribosomal lipopeptide with selective antimicrobial activity
against Gram-negative bacteria. Here we show that TriA1 exerts its bactericidal effect by …

Just over a million people died globally in 2019 due to antibiotic resistance caused by
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella …

Protein-peptide interactions are vital for the cell. They mediate, inhibit or serve as structural
components in nearly 40% of all macromolecular interactions, and are often associated with …

Cyclic β-sheet decapeptides from the tyrocidine group and the homologous gramicidin S
were the first commercially used antibiotics, yet it remains unclear exactly how they kill …

The number of antibiotic-resistant bacteria is increasing worldwide, and the demand for
novel antimicrobials is constantly growing. Antimicrobial peptides (AMPs) could be an …

Even before the perception or interaction with pathogens, plants rely on constitutively
guardian molecules, often specific to tissue or stage, with further expression after contact …

The ideal wound-healing scaffold should provide the appropriate physical and mechanical
properties to prevent secondary infection, as well as an excellent physiological environment …

Highlights•Insect cuticles are inhabited by diverse microorganisms.•Insect ectomicrobiomes
can mediate colonization resistance against fungal parasites.•Fungal pathogens can …

Antimicrobial peptides (AMPs) are natural antibiotics produced by virtually all living
organisms. Typically, AMPs are cationic and amphiphilic and first contacts with target …

Antimicrobial peptides, or AMPs, play a significant role in many environments as a tool to
remove competing organisms. In response, many bacteria have evolved mechanisms to …