Paneth cells at the base of small intestinal crypts of Lieberkühn secrete high levels of α-
defensins in response to cholinergic and microbial stimuli. Paneth cell α-defensins are …

Over the last years, antimicrobial peptides (AMPs) have been the focus of intense research
toward the finding of a viable alternative to current antifungal drugs. Defensins are one of the …

Antibiotics with multiple mechanisms of action and broad-spectrum are urgently required to
combat the growing health threat posed by resistant pathogenic microorganisms. Combining …

Antimicrobial resistance is a leading cause of mortality, calling for the development of new
antibiotics. The fungal antibiotic plectasin is a eukaryotic host defence peptide that blocks …

This review focuses on bacteria-fungi interactions mediated by secondary metabolites that
occur in the environment and have implications for medicine and biotechnology. Bipartite …

Pathogens resistant to most conventional anti-infectives are a harbinger of the need to
discover and develop novel anti-infective agents and strategies. Endogenous host defense …

A novel bacteriocin, plantaricin ZJ008 produced by Lactobacillus plantarum ZJ008 isolated
from fresh milk, was purified by XAD 2, cation exchange chromatograph, gel chromatograph …

Antimicrobial peptides and proteins (AMPs) are widespread in the living kingdom. They are
key effectors of defense reactions and mediators of competitions between organisms. They …

The rapid development of multidrug-resistant (MDR) bacteria due to the improper and
overuse of antibiotics and the ineffective performance of antibiotics against the difficult-to …

Antimicrobial therapy is the most applied method for treating and preventing bacterial
infection in livestock. However, it becomes less effective due to development of the …