Analysis of the mechanism of action of potent antibacterial hetero-tri-organometallic compounds: A structurally new class of antibiotics
Two hetero-tri-organometallic compounds with potent activity against Gram-positive bacteria
including multi-resistant Staphylococcus aureus (MRSA) were identified. The compounds …
including multi-resistant Staphylococcus aureus (MRSA) were identified. The compounds …
The new insights into the oyster antimicrobial defense: Cellular, molecular and genetic view
E Bachère, RD Rosa, P Schmitt, AC Poirier… - Fish & shellfish …, 2015 - Elsevier
Oysters are sessile filter feeders that live in close association with abundant and diverse
communities of microorganisms that form the oyster microbiota. In such an association …
communities of microorganisms that form the oyster microbiota. In such an association …
Targeting a cell wall biosynthesis hot spot
A Müller, A Klöckner, T Schneider - Natural product reports, 2017 - pubs.rsc.org
Covering: up to 2017 History points to the bacterial cell wall biosynthetic network as a very
effective target for antibiotic intervention, and numerous natural product inhibitors have been …
effective target for antibiotic intervention, and numerous natural product inhibitors have been …
Bacterial resistance mechanisms against host defense peptides
T Koprivnjak, A Peschel - Cellular and Molecular Life Sciences, 2011 - Springer
Host defense peptides and proteins are important components of the innate host defense
against pathogenic microorganisms. They target negatively charged bacterial surfaces and …
against pathogenic microorganisms. They target negatively charged bacterial surfaces and …
Cubosomes post-loaded with antimicrobial peptides: characterization, bactericidal effect and proteolytic stability
L Boge, A Umerska, N Matougui, H Bysell… - International journal of …, 2017 - Elsevier
Novel antibiotics, such as antimicrobial peptides (AMPs), have recently attended more and
more attraction. In this work, dispersed cubic liquid crystalline gel (cubosomes) was used as …
more attraction. In this work, dispersed cubic liquid crystalline gel (cubosomes) was used as …
The plant defensin RsAFP2 induces cell wall stress, septin mislocalization and accumulation of ceramides in Candida albicans
K Thevissen, P de Mello Tavares, D Xu… - Molecular …, 2012 - Wiley Online Library
The antifungal plant defensin RsAFP2 isolated from radish interacts with fungal
glucosylceramides and induces apoptosis in Candida albicans. To further unravel the …
glucosylceramides and induces apoptosis in Candida albicans. To further unravel the …
Computational tools for exploring sequence databases as a resource for antimicrobial peptides
Data mining has been recognized by many researchers as a hot topic in different areas. In
the post-genomic era, the growing number of sequences deposited in databases has been …
the post-genomic era, the growing number of sequences deposited in databases has been …
[HTML][HTML] Antimicrobial peptides with antiviral and anticancer properties and their modification and nanodelivery systems
Antimicrobial peptides (AMPs) are natural biopolymers in the host defense system. AMPs
display multiple functions against bacterial, fungal, and viral infection, as well as anticancer …
display multiple functions against bacterial, fungal, and viral infection, as well as anticancer …
Identification and in vitro Analysis of the GatD/MurT Enzyme-Complex Catalyzing Lipid II Amidation in Staphylococcus aureus
D Münch, T Roemer, SH Lee, M Engeser… - PLoS …, 2012 - journals.plos.org
The peptidoglycan of Staphylococcus aureus is characterized by a high degree of
crosslinking and almost completely lacks free carboxyl groups, due to amidation of the D …
crosslinking and almost completely lacks free carboxyl groups, due to amidation of the D …
Fmoc solid-phase peptide synthesis
PR Hansen, A Oddo - Peptide antibodies: Methods and protocols, 2015 - Springer
Synthetic peptides are important as drugs and in research. Currently, the method of choice
for producing these compounds is solid-phase peptide synthesis. In this nonspecialist …
for producing these compounds is solid-phase peptide synthesis. In this nonspecialist …