Analysis of the mechanism of action of potent antibacterial hetero-tri-organometallic compounds: A structurally new class of antibiotics

M Wenzel, M Patra, CHR Senges, I Ott… - ACS chemical …, 2013 - ACS Publications
Two hetero-tri-organometallic compounds with potent activity against Gram-positive bacteria
including multi-resistant Staphylococcus aureus (MRSA) were identified. The compounds …

The new insights into the oyster antimicrobial defense: Cellular, molecular and genetic view

E Bachère, RD Rosa, P Schmitt, AC Poirier… - Fish & shellfish …, 2015 - Elsevier
Oysters are sessile filter feeders that live in close association with abundant and diverse
communities of microorganisms that form the oyster microbiota. In such an association …

Targeting a cell wall biosynthesis hot spot

A Müller, A Klöckner, T Schneider - Natural product reports, 2017 - pubs.rsc.org
Covering: up to 2017 History points to the bacterial cell wall biosynthetic network as a very
effective target for antibiotic intervention, and numerous natural product inhibitors have been …

Bacterial resistance mechanisms against host defense peptides

T Koprivnjak, A Peschel - Cellular and Molecular Life Sciences, 2011 - Springer
Host defense peptides and proteins are important components of the innate host defense
against pathogenic microorganisms. They target negatively charged bacterial surfaces and …

Cubosomes post-loaded with antimicrobial peptides: characterization, bactericidal effect and proteolytic stability

L Boge, A Umerska, N Matougui, H Bysell… - International journal of …, 2017 - Elsevier
Novel antibiotics, such as antimicrobial peptides (AMPs), have recently attended more and
more attraction. In this work, dispersed cubic liquid crystalline gel (cubosomes) was used as …

The plant defensin RsAFP2 induces cell wall stress, septin mislocalization and accumulation of ceramides in Candida albicans

K Thevissen, P de Mello Tavares, D Xu… - Molecular …, 2012 - Wiley Online Library
The antifungal plant defensin RsAFP2 isolated from radish interacts with fungal
glucosylceramides and induces apoptosis in Candida albicans. To further unravel the …

Computational tools for exploring sequence databases as a resource for antimicrobial peptides

WF Porto, AS Pires, OL Franco - Biotechnology advances, 2017 - Elsevier
Data mining has been recognized by many researchers as a hot topic in different areas. In
the post-genomic era, the growing number of sequences deposited in databases has been …

[HTML][HTML] Antimicrobial peptides with antiviral and anticancer properties and their modification and nanodelivery systems

M Yang, S Liu, C Zhang - Current Research in Biotechnology, 2023 - Elsevier
Antimicrobial peptides (AMPs) are natural biopolymers in the host defense system. AMPs
display multiple functions against bacterial, fungal, and viral infection, as well as anticancer …

Identification and in vitro Analysis of the GatD/MurT Enzyme-Complex Catalyzing Lipid II Amidation in Staphylococcus aureus

D Münch, T Roemer, SH Lee, M Engeser… - PLoS …, 2012 - journals.plos.org
The peptidoglycan of Staphylococcus aureus is characterized by a high degree of
crosslinking and almost completely lacks free carboxyl groups, due to amidation of the D …

Fmoc solid-phase peptide synthesis

PR Hansen, A Oddo - Peptide antibodies: Methods and protocols, 2015 - Springer
Synthetic peptides are important as drugs and in research. Currently, the method of choice
for producing these compounds is solid-phase peptide synthesis. In this nonspecialist …