Takotsubo Syndrome (TTS) is a condition of transient left ventricular dysfunction that is
typically triggered by emotional or physical stress. Since first described in Japan in 1990, it …

Driven by autonomous molecular clocks that are synchronized by a master pacemaker in the
suprachiasmatic nucleus, cardiac physiology fluctuates in diurnal rhythms that can be partly …

Myocardial ischemia with no obstructive coronary arteries (INOCA) is a chronic coronary
syndrome condition that is increasingly being recognized as a substantial contributor to …

Herba Epimedii is a famous herb collected from China and Korea. It has been used for
impotency, osteoporosis, and amnestic treatment for thousands of years. Icariin, a typical …

In acute sympathetic stress, catecholamine overload can lead to stress cardiomyopathy. We
tested the hypothesis that cardiomyocyte NOX4 (NADPH oxidase 4)-dependent …

Objective The advantage of beta-blockers has been postulated in patients with Takotsubo
syndrome (TTS) given the pathophysiological role of catecholamines. We hypothesised that …

Purpose Cardiac autonomic dysfunction is one of the main pillars of cardiovascular
pathophysiology. The purpose of this review is to provide an overview of the current state of …

Sex is a key risk factor for many types of cardiovascular disease. It is imperative to
understand the mechanisms underlying sex differences to devise optimal preventive and …

Cardiovascular diseases (CVD) remain the leading cause of mortality worldwide. Although
major diagnostic and therapeutic advances have significantly improved the prognosis of …

Heart failure is a clinical syndrome where cardiac output is not sufficient to sustain adequate
perfusion and normal bodily functions, initially during exercise and in more severe forms …