The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells

I Riahi-Chebbi, S Souid, H Othman, M Haoues… - Scientific reports, 2019 - nature.com
Resistance to 5-Fluorouracil chemotherapy is a major cause of therapeutic failure in colon
cancer cure. Development of combined therapies constitutes an effective strategy to inhibit …

Mechanisms of chemopreventive and therapeutic proprieties of ginger extracts in cancer

M Zadorozhna, D Mangieri - International journal of molecular sciences, 2021 - mdpi.com
Ginger (Zingiber officinale Roscoe, family: Zingiberaceae), originating in South-East Asia, is
one of the most used spices and condiments for foods and beverages. It is also used in …

Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer

M Hijaz, S Das, I Mert, A Gupta, Z Al-Wahab, C Tebbe… - BMC cancer, 2016 - Springer
Background Nanomedicine is a very promising field and nanomedical drugs have recently
been used as therapeutic agents against cancer. In a previous study, we showed that …

[HTML][HTML] Epithelial-to-endothelial transition and cancer stem cells: two cornerstones of vasculogenic mimicry in malignant tumors

B Sun, D Zhang, N Zhao, X Zhao - Oncotarget, 2017 - ncbi.nlm.nih.gov
Vasculogenic mimicry (VM) is a functional microcirculation pattern in malignant tumors
accompanied by endothelium-dependent vessels and mosaic vessels. VM has been …

Current understanding of flavonoids in cancer therapy and prevention

M Farhan, A Rizvi, M Aatif, A Ahmad - Metabolites, 2023 - mdpi.com
Cancer is a major cause of death worldwide, with multiple pathophysiological
manifestations. In particular, genetic abnormalities, inflammation, bad eating habits …

LncRNA DANCR promotes tumor growth and angiogenesis in ovarian cancer through direct targeting of miR‐145

X Lin, F Yang, X Qi, Q Li, D Wang, T Yi… - Molecular …, 2019 - Wiley Online Library
Differentiation antagonizing non‐protein coding RNA (DANCR) is a newly identified
oncogenic long noncoding RNA found in various cancers. However, the functional role of …

Regulation of tumor angiogenesis by microRNAs: State of the art

NH Goradel, N Mohammadi… - Journal of cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs, miRs) are small (21–25 nucleotides) endogenous and noncoding
RNAs involved in many cellular processes such as apoptosis, development, proliferation …

[HTML][HTML] Melatonin as a potential anticarcinogen for non-small-cell lung cancer

Z Ma, Y Yang, C Fan, J Han, D Wang, S Di, W Hu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Non-small-cell lung cancer (NSCLC) is a leading cause of death from cancer worldwide.
Melatonin, an indoleamine discovered in the pineal gland, exerts pleiotropic anticancer …

Calcium signalling pathways in prostate cancer initiation and progression

R Silvestri, V Nicolì, P Gangadharannambiar… - Nature Reviews …, 2023 - nature.com
Cancer cells proliferate, differentiate and migrate by repurposing physiological signalling
mechanisms. In particular, altered calcium signalling is emerging as one of the most …

Therapeutic potentials of Apatinib in cancer treatment: Possible mechanisms and clinical relevance

NF Maroufi, MR Rashidi, V Vahedian, M Akbarzadeh… - Life Sciences, 2020 - Elsevier
Metastasis is one of the main issues in cancer treatment and it has been documented that
angiogenesis plays an important role in this process. Studies showed that vascular …