Interaction of the T cell receptor (TCR) with an MHC-antigenic peptide complex results in
changes at the molecular and cellular levels in T cells. The outside environmental cues are …

The main breakthrough in tumor immunotherapy was the discovery of immune checkpoint
(IC) proteins, which act as a potent suppressor of the immune system by a myriad of …

Hepatocellular carcinoma (HCC) remains the sixth most commonly diagnosed malignancy
worldwide, still representing an important cause of cancer-related death. Over the next few …

Introduction Hepatocellular carcinoma (HCC) represents the sixth most commonly
diagnosed malignancy worldwide, accounting for millions of deaths annually. Despite …

Despite being an integral part of the immune response in the tumor microenvironment
(TME), few studies have mechanistically elucidated eosinophil functions in cancer …

Nipah virus (NiV) is an emerging highly lethal zoonotic disease that, like SARS-CoV-2, can
be transmitted via respiratory droplets. Single-injection vaccines that rapidly control NiV …

Immunotherapy is a new pillar of cancer therapy that provides novel opportunities to treat
solid tumors. In this context, the development of new drugs targeting immune checkpoints is …

Cancer is the second leading cause of death worldwide. Traditional approaches, such as
surgery, chemotherapy, and radiotherapy have been the main cancer therapeutic modalities …

Background Comprehensive antitumor therapy through integrated multimodal means has
drawn increasing attention owing to its high efficiency and metastasis suppression. Results …

The significance of Akkermansia bacteria presence in gut micobiome, mainly Akkermansia
mucinifila, is currently being investigated in the context of supporting therapy and marker for …