[HTML][HTML] The role of curcumin in cancer treatment
Curcumin is a polyphenol extracted from the rhizomes of the turmeric plant, Curcuma longa
which has anti-inflammatory, and anticancer properties. Chronic inflammation is associated …
which has anti-inflammatory, and anticancer properties. Chronic inflammation is associated …
[HTML][HTML] Cancer chemoprevention: A strategic approach using phytochemicals
M Swetha, CK Keerthana, TP Rayginia… - Frontiers in …, 2022 - frontiersin.org
Cancer chemoprevention approaches are aimed at preventing, delaying, or suppressing
tumor incidence using synthetic or natural bioactive agents. Mechanistically …
tumor incidence using synthetic or natural bioactive agents. Mechanistically …
NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo
G Jia, Y Han, Y An, Y Ding, C He, X Wang, Q Tang - Biomaterials, 2018 - Elsevier
Currently, glioma treatment is limited by two main factors: timely detection at onset or relapse
and restriction of drugs by the blood–brain barrier (BBB) from entering the brain and …
and restriction of drugs by the blood–brain barrier (BBB) from entering the brain and …
[HTML][HTML] Antioxidants in brain tumors: current therapeutic significance and future prospects
X Qi, SK Jha, NK Jha, S Dewanjee, A Dey, R Deka… - Molecular Cancer, 2022 - Springer
Brain cancer is regarded among the deadliest forms of cancer worldwide. The distinct tumor
microenvironment and inherent characteristics of brain tumor cells virtually render them …
microenvironment and inherent characteristics of brain tumor cells virtually render them …
[HTML][HTML] AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox …
TC Chen, JY Chuang, CY Ko, TJ Kao, PY Yang, CH Yu… - Redox biology, 2020 - Elsevier
Drug resistance is the main obstacle in the improvement of chemotherapeutic efficacy in
glioblastoma. Previously, we showed that dehydroepiandrosterone (DHEA), one kind of …
glioblastoma. Previously, we showed that dehydroepiandrosterone (DHEA), one kind of …
[HTML][HTML] Free radicals as a double-edged sword: The cancer preventive and therapeutic roles of curcumin
Free radicals, generally composed of reactive oxygen species (ROS) and reactive nitrogen
species (RNS), are generated in the body by various endogenous and exogenous systems …
species (RNS), are generated in the body by various endogenous and exogenous systems …
ROS‐mediated cancer cell killing through dietary phytochemicals
S NavaneethaKrishnan, JL Rosales… - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) promote carcinogenesis by inducing genetic mutations,
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …
[HTML][HTML] The challenge of targeting cancer stem cells to halt metastasis
A Agliano, A Calvo, C Box - Seminars in Cancer Biology, 2017 - Elsevier
Despite a continuing debate about the existence of cancer stem cells (CSCs), recent
discoveries have provided further support for their existence and their roles in drug …
discoveries have provided further support for their existence and their roles in drug …
[HTML][HTML] Anticancer mechanism of curcumin on human glioblastoma
SC Wong, MNA Kamarudin, R Naidu - Nutrients, 2021 - mdpi.com
Glioblastoma (GBM) is the most malignant brain tumor and accounts for most adult brain
tumors. Current available treatment options for GBM are multimodal, which include surgical …
tumors. Current available treatment options for GBM are multimodal, which include surgical …
Curcumin-A promising nutritional strategy for chronic kidney disease patients
L de Almeida Alvarenga, V de Oliveira Leal… - Journal of Functional …, 2018 - Elsevier
Many studies have been conducted to identify therapeutic strategies to modulate
inflammation and oxidative stress, complications that contribute to the increased morbidity …
inflammation and oxidative stress, complications that contribute to the increased morbidity …