A comprehensive review of the global efforts on COVID-19 vaccine development
Y Li, R Tenchov, J Smoot, C Liu, S Watkins… - ACS Central …, 2021 - ACS Publications
A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development | ACS
Central Science ACS ACS Publications C&EN CAS Find my institution Blank image Log In ACS …
Central Science ACS ACS Publications C&EN CAS Find my institution Blank image Log In ACS …
Self-assembled mRNA vaccines
Abstract mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-
19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology …
19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology …
Nanopore native RNA sequencing of a human poly (A) transcriptome
High-throughput complementary DNA sequencing technologies have advanced our
understanding of transcriptome complexity and regulation. However, these methods lose …
understanding of transcriptome complexity and regulation. However, these methods lose …
A comprehensive review of mRNA vaccines
mRNA vaccines have been demonstrated as a powerful alternative to traditional
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …
Alternative cleavage and polyadenylation in health and disease
Most human genes have multiple sites at which RNA 3ʹ end cleavage and polyadenylation
can occur, enabling the expression of distinct transcript isoforms under different conditions …
can occur, enabling the expression of distinct transcript isoforms under different conditions …
The challenge and prospect of mRNA therapeutics landscape
Messenger RNA (mRNA)-based therapeutics hold the potential to cause a major revolution
in the pharmaceutical industry because they can be used for precise and individualized …
in the pharmaceutical industry because they can be used for precise and individualized …
Alternative polyadenylation of mRNA precursors
Alternative polyadenylation (APA) is an RNA-processing mechanism that generates distinct
3′ termini on mRNAs and other RNA polymerase II transcripts. It is widespread across all …
3′ termini on mRNAs and other RNA polymerase II transcripts. It is widespread across all …
Nanomedicines to deliver mRNA: state of the art and future perspectives
I Gómez-Aguado, J Rodríguez-Castejón… - Nanomaterials, 2020 - mdpi.com
The use of messenger RNA (mRNA) in gene therapy is increasing in recent years, due to its
unique features compared to plasmid DNA: Transient expression, no need to enter into the …
unique features compared to plasmid DNA: Transient expression, no need to enter into the …
Poly (A)-tail profiling reveals an embryonic switch in translational control
AO Subtelny, SW Eichhorn, GR Chen, H Sive… - Nature, 2014 - nature.com
Poly (A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but
difficulties in globally measuring poly (A)-tail lengths have impeded greater understanding of …
difficulties in globally measuring poly (A)-tail lengths have impeded greater understanding of …
Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics: Getting the message across
AK Minnaert, H Vanluchene, R Verbeke… - Advanced drug delivery …, 2021 - Elsevier
The recent approval of messenger RNA (mRNA)-based vaccines to combat the SARS-CoV-
2 pandemic highlights the potential of both conventional mRNA and self-amplifying mRNA …
2 pandemic highlights the potential of both conventional mRNA and self-amplifying mRNA …