[HTML][HTML] miRNA studies in glaucoma: a comprehensive review of current knowledge and future perspectives

M Dobrzycka, A Sulewska, P Biecek… - International Journal of …, 2023 - mdpi.com
Glaucoma, a neurodegenerative disorder that leads to irreversible blindness, remains a
challenge because of its complex nature. MicroRNAs (miRNAs) are crucial regulators of …

Roles of non‐coding RNAs in eye development and diseases

X Shi, Z Xue, K Ye, J Yuan, Y Zhang… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
The prevalence of ocular disorders is dramatically increasing worldwide, especially those
that cause visual impairment and permanent loss of vision, including cataract, glaucoma …

[HTML][HTML] The application of micrornas in glaucoma research: a bibliometric and visualized analysis

R Zhang, Y Tao, J Huang - International Journal of Molecular Sciences, 2023 - mdpi.com
Glaucoma is similar to a neurodegenerative disorder and leads to global irreversible loss of
vision. Despite extensive research, the pathophysiological mechanisms of glaucoma remain …

[HTML][HTML] The interplay between metabolites and microRNAs in aqueous humor to coordinate corneal endothelium integrity

M Ueno, K Yoshii, T Yamashita, K Sonomura… - Ophthalmology …, 2023 - Elsevier
Purpose The purpose of the study was to clarify the interplay between metabolites and
microRNAs (miRs) in the aqueous humor (AqH) of bullous keratopathy (BK) patients to …

[HTML][HTML] A bibliometric analysis of the application of stem cells in glaucoma research from 1999 to 2022

Y Tao, Q Zhang, M Meng, J Huang - Frontiers in Cell and …, 2023 - frontiersin.org
Background: Glaucoma, a neurodegenerative disease of the retina, is the leading cause of
irreversible blindness. Stem cells have therapeutic potential for glaucoma. However, few …

[HTML][HTML] Expression of microRNAs related to apoptosis in the aqueous humor and lens capsule of patients with glaucoma

HS Yu, EH Hong, JH Kang, YW Lee, WJ Lee… - Frontiers in …, 2024 - frontiersin.org
Background The aim of this study is to investigate the expression profiles of microRNAs
(miRNAs) related to apoptosis in the aqueous humor (AH) and lens capsule (LC) of patients …

Epigenetic mechanisms of non-retinal components of the aging eye and novel therapeutic strategies

M Lamas - Experimental Eye Research, 2023 - Elsevier
The eye is a complex organ composed of various cell types, each serving a unique purpose.
However, aging brings about structural and functional changes in these cells, leading to …

[HTML][HTML] Neuroprotection of rodent and human retinal ganglion cells in vitro/ex vivo by the hybrid small molecule SA-2

JH Pham, GA Johnson, RS Rangan, CE Amankwa… - Cells, 2022 - mdpi.com
The mechanisms underlying the neuroprotective effects of the hybrid antioxidant-nitric oxide
donating compound SA-2 in retinal ganglion cell (RGC) degeneration models were …

miR-196b-5p regulates inflammatory process and migration via targeting Nras in trabecular meshwork cells

J Zhang, X Yang, Y Zong, T Yu, X Yang - International …, 2024 - Elsevier
Glaucoma, an insidious ophthalmic pathology, is typified by an aberrant surge in intraocular
pressure (IOP) which culminates in the degeneration of retinal ganglion cells and optical …

[HTML][HTML] Exploring Early-Stage Retinal Neurodegeneration in Murine Pigmentary Glaucoma: Insights From Gene Networks and miRNA Regulation Analyses

Q Gu, A Kumar, M Hook, F Xu… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: Glaucoma is a group of heterogeneous optic neuropathies characterized by the
progressive degeneration of retinal ganglion cells. However, the underlying mechanisms …