Nanodiamonds are novel nanosized carbon building blocks possessing varied fascinating
mechanical, chemical, optical and biological properties, making them significant active …

Fc‐Fusion proteins represent a successful class of biopharmaceutical products, with already
13 drugs approved in the European Union and United States as well as three biosimilar …

Comprehensive profiling of humoral antibody response to severe acute respiratory
syndrome (SARS) coronavirus-2 (CoV-2) proteins is essential in understanding the host …

The development of recombinant therapeutic proteins has been a major revolution in
modern medicine. Therapeutic-based monoclonal antibodies (mAbs) are growing rapidly …

Accelerated development of new therapeutics in an increasingly competitive landscape
requires the use of high throughput analytical platforms. In addition, the complexity of novel …

Alterations of protein glycosylation can serve as sensitive and specific disease biomarkers.
Labeling procedures for improved separation and detectability of oligosaccharides have …

N-glycosylation of therapeutic antibodies starts as a co-translational step followed by a set of
post-translational modifications and is considered as one of the critical quality attributes …

Glycosylation can be a critical quality attribute in biologic manufacturing. In particular, it has
implications on the half‐life, immunogenicity, and pharmacokinetics of therapeutic …

The Consortium for Top-Down Proteomics (www. topdownproteomics. org) launched the
present study to assess the current state of top-down mass spectrometry (TD MS) and …

Oligomerization and glycosylation modulate therapeutic glycoprotein stability and efficacy.
The interplay between these two critical attributes on therapeutic glycoproteins, is however …