Dengue, caused by four closely related viruses, is a growing global public health concern,
with outbreaks capable of overwhelming health-care systems and disrupting economies …

Antibodies have been used to prevent or treat viral infections since the nineteenth century,
but the full potential to use passive immunization for infectious diseases has yet to be …

Sequential infection with multiple dengue virus (DENV) serotypes is thought to induce
enduring protection against dengue disease. However, long-term antibody waning has been …

Zika virus (ZIKV) is a mosquito-borne flavivirus that can vertically transmit from mother to
fetus, potentially causing congenital defects, including microcephaly. It is not fully …

The fight against infectious diseases calls for the development of safe and effective vaccines
that generate long-lasting protective immunity. In a few situations, vaccine-mediated immune …

Background: Dengue virus is a flavivirus transmitted by Aedes mosquitoes and is an
important cause of illness worldwide. Data on the severity of travel-associated dengue …

Flaviviruses cause a spectrum of potentially severe diseases. Most flaviviruses are
transmitted by mosquitoes or ticks and are widely distributed all over the world. Among them …

Infection with any of the four dengue virus serotypes (DENV1–4) can protect against or
enhance subsequent dengue depending on pre-existing antibodies and the subsequent …

Abstract Background Travel to Southeast Asia increases the likelihood of acquiring mosquito-
borne Flavivirus infections such as dengue (DENV), Japanese encephalitis (JEV) and Zika …

Monoclonal antibodies (mAb) against the envelope (E) protein of Zika virus (ZIKV) have
shown great potential as therapeutics against the Zika epidemics. However, their use as a …