Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …

Connective tissue growth factor (CTGF) is a key signaling and regulatory molecule involved
in different biological processes, such as cell proliferation, angiogenesis, and wound …

Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

Aptamers are promising therapeutic and diagnostic agents for various diseases due to their
high affinity and specificity against target proteins. Structural determination in combination …

Osteoporosis is a systemic skeletal disease that is a cause of morbidity and mortality. It can
affect all ages but most frequently postmenopausal women. It is a silent condition, however …

Sclerostin, a protein secreted from osteocytes, negatively regulates the WNT signaling
pathway by binding to the LRP5/6 co-receptors and further inhibits bone formation and …

The lack of drugs that target both disease progression and tissue preservation makes it
difficult to effectively manage rheumatoid arthritis (RA). Here, we report a porous silicon …

Osteoporosis is a chronical, systemic skeletal disorder characterized by an increase in bone
resorption, which leads to reduced bone density. The reduction in bone mineral density and …

The bone extracellular matrix (ECM) contains minerals deposited on highly crosslinked
collagen fibrils and hundreds of non-collagenous proteins. Some of these proteins are key to …

Simple Summary Osteoporosis is a prevalent condition affecting 200 million individuals
world-wide. Estimates are about one in three women will experience a fragility fracture of …