Cancers are highly complex diseases that are characterized by not only the overgrowth of
malignant cells but also an altered immune response. The inhibition and reprogramming of …

Tumor immune microenvironment (TIME) include tumor cells, immune cells, cytokines, etc.
The interactions between these components, which are divided into anti-tumor and pro …

Targeting ferroptosis, which provokes lipid peroxidation in cancer cells, presents potentially
new avenues for anticancer therapy. Recent studies have begun to explore how immune …

Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …

The term ferroptosis was put forward in 2012 and has been researched exponentially over
the past few years. Ferroptosis is an unconventional pattern of iron-dependent programmed …

Abstract ABSTRACT: Colony-Stimulating Factor-1 Receptor (CSF1R) is a receptor tyrosine
kinase that controls the differentiation and maintenance of most tissue-resident …

Macrophages are the most abundant and one of the most critical cells of tumor immunity.
They provide a bridge between innate and adaptive immunity through releasing cytokines …

In cancer treatment, the recurrent challenge of inducing apoptosis through conventional
therapeutic modalities, often thwarted by therapy resistance, emphasizes the critical need to …

Introduction Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) is a highly
personalized type of cancer immunotherapy. TIL-based ACT exploits naturally occurring …

Nanoscale artificial antigen-presenting cells (aAPCs) are promising to activate T cells
directly for cancer immunotherapy, while feasible and flexible strategy to develop nanoscale …