Ferroptosis is a recently recognized iron-dependent form of non-apoptotic regulated cell
death (RCD) characterized by lipid peroxide accumulation to lethal levels. Cancer cells …

Tumor-associated macrophages (TAMs) play a pivotal role in the tumor microenvironment,
influencing cancer progression and contributing to poor prognosis. However, in cervical …

Macrophages represent an important component of the innate immune system. Under
physiological conditions, macrophages, which are essential phagocytes, maintain a …

Macrophages play a major role in maintaining an organism's physiology, such as
development, homeostasis, tissue repair, and immunity. These immune cells are known to …

胆囊癌(gallbladder cancer, GBC) 是一种常见的胆道系统恶性肿瘤, 往往预后不良, 晚期患者的5
年生存率不到10%, 手术是唯一有效的治疗方法. 肿瘤微环境(tumor microenvironment, TME) …

Background/Aim: Bone marrow-derived cells regulate the antitumor functions of tumor
infiltrating lymphocytes (TILs) through arginase 1 (ARG1)-dependent metabolism. This study …

Abstract The Colony-Stimulating Factor 1 (CSF-1) and its receptor (CSF1R) constitute an
important axis that regulates the phenotype of most tissue-resident macrophages …

Modern medicine has yet to produce selective treatments for the vast majority of cancer
types. Most chemotherapies, though complex, remain non-specific, and thus destroy healthy …

The role of the immune system in tumor progression has been the subject of research for
more than 100 years since Paul Ehrlich hypothesized that the presence of the immune …

Plattenepithelkarzinome der Kopf-Hals-Region (head and neck squamous cell carcinoma,
HNSCC) stellen mit jährlich 550.000 neu diagnostizierten Erkrankungen und 380.000 …