The second wave of synthetic biology: from modules to systems

PEM Purnick, R Weiss - Nature reviews Molecular cell biology, 2009 - nature.com
Synthetic biology is a research field that combines the investigative nature of biology with
the constructive nature of engineering. Efforts in synthetic biology have largely focused on …

Engineering microbial consortia: a new frontier in synthetic biology

K Brenner, L You, FH Arnold - Trends in biotechnology, 2008 - cell.com
Microbial consortia are ubiquitous in nature and are implicated in processes of great
importance to humans, from environmental remediation and wastewater treatment to …

Improving fatty acids production by engineering dynamic pathway regulation and metabolic control

P Xu, L Li, F Zhang… - Proceedings of the …, 2014 - National Acad Sciences
Global energy demand and environmental concerns have stimulated increasing efforts to
produce carbon-neutral fuels directly from renewable resources. Microbially derived …

The acetate switch

AJ Wolfe - Microbiology and molecular biology reviews, 2005 - Am Soc Microbiol
To succeed, many cells must alternate between life-styles that permit rapid growth in the
presence of abundant nutrients and ones that enhance survival in the absence of those …

Synthetic biology: new engineering rules for an emerging discipline

E Andrianantoandro, S Basu, DK Karig… - Molecular systems …, 2006 - embopress.org
Synthetic biologists engineer complex artificial biological systems to investigate natural
biological phenomena and for a variety of applications. We outline the basic features of …

Programmed population control by cell–cell communication and regulated killing

L You, RS Cox Iii, R Weiss, FH Arnold - Nature, 2004 - nature.com
De novo engineering of gene circuits inside cells is extremely difficult,,,,,,,,, and efforts to
realize predictable and robust performance must deal with noise in gene expression and …

Programmable cells: interfacing natural and engineered gene networks

H Kobayashi, M Kaern, M Araki… - Proceedings of the …, 2004 - National Acad Sciences
Novel cellular behaviors and characteristics can be obtained by coupling engineered gene
networks to the cell's natural regulatory circuitry through appropriately designed input and …

Molecular communication and nanonetwork for targeted drug delivery: A survey

UAK Chude-Okonkwo, R Malekian… - … Surveys & Tutorials, 2017 - ieeexplore.ieee.org
Molecular communication (MC) and molecular network (MN) are communication paradigms
that use biochemical signaling to achieve information exchange among naturally and …

Synthetic biology—putting engineering into biology

M Heinemann, S Panke - Bioinformatics, 2006 - academic.oup.com
Synthetic biology is interpreted as the engineering-driven building of increasingly complex
biological entities for novel applications. Encouraged by progress in the design of artificial …

A synthetic gene–metabolic oscillator

E Fung, WW Wong, JK Suen, T Bulter, S Lee, JC Liao - Nature, 2005 - nature.com
Autonomous oscillations found in gene expression and metabolic, cardiac and neuronal
systems,,, have attracted significant attention both because of their obvious biological roles …