[HTML][HTML] CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances
In the last decade, Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a
promising immunotherapeutic approach to fight cancers. This approach consists of …
promising immunotherapeutic approach to fight cancers. This approach consists of …
[HTML][HTML] CAR-NK cells in the treatment of solid tumors
E Wrona, M Borowiec, P Potemski - International journal of molecular …, 2021 - mdpi.com
CAR-T (chimeric antigen receptor T) cells have emerged as a milestone in the treatment of
patients with refractory B-cell neoplasms. However, despite having unprecedented efficacy …
patients with refractory B-cell neoplasms. However, despite having unprecedented efficacy …
[HTML][HTML] Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma
Chimeric antigen receptor (CAR) therapy is a promising immunotherapeutic strategy for
treating multiple refractory blood cancers, but further advances are required for solid tumor …
treating multiple refractory blood cancers, but further advances are required for solid tumor …
[HTML][HTML] Overcoming tumor resistance mechanisms in CAR-NK cell therapy
A Valeri, A García-Ortiz, E Castellano… - Frontiers in …, 2022 - frontiersin.org
Despite the impressive results of autologous CAR-T cell therapy in refractory B
lymphoproliferative diseases, CAR-NK immunotherapy emerges as a safer, faster, and cost …
lymphoproliferative diseases, CAR-NK immunotherapy emerges as a safer, faster, and cost …
[HTML][HTML] Advancements in CAR-NK therapy: lessons to be learned from CAR-T therapy
MK Kilgour, DJ Bastin, SH Lee, M Ardolino… - Frontiers in …, 2023 - frontiersin.org
Advancements in chimeric antigen receptor engineered T-cell (CAR-T) therapy have
revolutionized treatment for several cancer types over the past decade. Despite this success …
revolutionized treatment for several cancer types over the past decade. Despite this success …
Current progress of chimeric antigen receptor (CAR) T versus CAR NK cell for immunotherapy of solid tumors
Equipping cancer-fighting immune cells with chimeric antigen receptor (CAR) has gained
immense attention for cancer treatment. CAR-engineered T cells (CAR T cells) are the first …
immense attention for cancer treatment. CAR-engineered T cells (CAR T cells) are the first …
[HTML][HTML] Chimeric antigen receptor-engineered NK cells: new weapons of cancer immunotherapy with great potential
X Wang, X Yang, X Yuan, W Wang, Y Wang - Experimental Hematology & …, 2022 - Springer
Chimeric antigen receptor (CAR)-engineered T (CAR-T) cells have obtained prominent
achievement in the clinical immunotherapy of hematological malignant tumors, leading to a …
achievement in the clinical immunotherapy of hematological malignant tumors, leading to a …
[HTML][HTML] Innovative strategies to improve the clinical application of NK cell-based immunotherapy
Natural killer cells constitute a part of the innate immune system that mediates an effective
immune response towards virus-infected and malignant cells. In recent years, research has …
immune response towards virus-infected and malignant cells. In recent years, research has …
[HTML][HTML] Recent findings on chimeric antigen receptor (CAR)-engineered immune cell therapy in solid tumors and hematological malignancies
A Keshavarz, A Salehi, S Khosravi, Y Shariati… - Stem Cell Research & …, 2022 - Springer
Advancements in adoptive cell therapy over the last four decades have revealed various
new therapeutic strategies, such as chimeric antigen receptors (CARs), which are dedicated …
new therapeutic strategies, such as chimeric antigen receptors (CARs), which are dedicated …
IGSF8 is an innate immune checkpoint and cancer immunotherapy target
Y Li, X Wu, C Sheng, H Liu, H Liu, Y Tang, C Liu… - Cell, 2024 - cell.com
Antigen presentation defects in tumors are prevalent mechanisms of adaptive immune
evasion and resistance to cancer immunotherapy, whereas how tumors evade innate …
evasion and resistance to cancer immunotherapy, whereas how tumors evade innate …