Human papillomavirus infection requires the CCT chaperonin complex

M Bugnon Valdano, P Massimi, J Broniarczyk… - Journal of …, 2021 - Am Soc Microbiol
Human papillomavirus (HPV) infection is a multistep process that implies complex
interactions of the viral particles with cellular proteins. The HPV capsid includes the two …

Enterovirus‐A71 exploits peripherin and Rac1 to invade the central nervous system

ZQ Lim, QY Ng, Y Oo, JJH Chu, SY Ng, SK Sze… - EMBO …, 2021 - embopress.org
Abstract Enterovirus‐A71 (EV‐A71) has been associated with severe neurological forms of
hand, foot, and mouth disease (HFMD). EV‐A71 infects motor neurons at neuromuscular …

[HTML][HTML] Comparative Subcellular Proteomics Analysis of Susceptible and Near-isogenic Resistant Bombyx mori (Lepidoptera) Larval Midgut Response to BmNPV …

X Wang, H Yu, J Xu, S Zhang, D Yu, M Liu, L Wang - Scientific Reports, 2017 - nature.com
The molecular mechanism of silkworm resistance to Bombyx mori nucleopolyhedrovirus
(BmNPV) infection remains largely unclear. Accumulating evidence suggests that …

[HTML][HTML] Rabies virus infection induces microtubule depolymerization to facilitate viral RNA synthesis by upregulating HDAC6

J Zan, S Liu, DN Sun, KK Mo, Y Yan, J Liu… - Frontiers in cellular …, 2017 - frontiersin.org
Rabies virus (RABV) is the cause of rabies, and is associated with severe neurological
symptoms, high mortality rate, and a serious threat to human health. Although cellular …

[HTML][HTML] Pathogenicity and tissue distribution of grass carp reovirus after intraperitoneal administration

HR Liang, YG Li, WW Zeng, YY Wang, Q Wang, SQ Wu - Virology journal, 2014 - Springer
Grass carp reovirus (GCRV) is the causative agent of grass carp hemorrhage and causes
significant loss of fingerlings. However, little is known about how the virus is distributed in …

[HTML][HTML] Requirement of cellular protein CCT7 for the replication of fowl adenovirus serotype 4 (FAdV-4) in leghorn male hepatocellular cells via interaction with the …

J Gao, M Zhao, X Duan, Y Wang, H Cao, X Li… - Viruses, 2019 - mdpi.com
Fowl adenovirus serotype 4 (FAdV-4) causes hepatitis-hydropericardium syndrome (HHS),
leading to severe economic losses in the poultry industry. Although the pathogenesis of …

[HTML][HTML] The co-chaperone Cdc37 regulates the rabies virus phosphoprotein stability by targeting to Hsp90AA1 machinery

Y Xu, F Liu, J Liu, D Wang, Y Yan, S Ji, J Zan, J Zhou - Scientific reports, 2016 - nature.com
Cdc37, as a kinase-specific co-chaperone of the chaperone Hsp90AA1 (Hsp90), actively
aids with the maturation, stabilization and activation of the cellular or viral kinase/kinase-like …

[HTML][HTML] Rabies virus phosphoprotein P5 binding to BECN1 regulates self-replication by BECN1-mediated autophagy signaling pathway

J Liu, M Liao, Y Yan, H Yang, H Wang… - Cell communication and …, 2020 - Springer
Background Rabies virus (RABV) is reported to encode five phosphoproteins (P), which are
involved in viral genomic replication, axonal transport, oxidative stress, interferon …

The chaperonin TRiC/CCT is essential for the action of bacterial glycosylating protein toxins like Clostridium difficile toxins A and B

M Steinemann, A Schlosser, T Jank… - Proceedings of the …, 2018 - National Acad Sciences
Various bacterial protein toxins, including Clostridium difficile toxins A (TcdA) and B (TcdB),
attack intracellular target proteins of host cells by glucosylation. After receptor binding and …

Chaperonin CCT5 binding with porcine parvovirus NS1 promotes the interaction of NS1 and COPƐ to facilitate viral replication

Q Du, X Zhang, N Xu, M Ma, B Miao, Y Huang… - Veterinary …, 2022 - Elsevier
Porcine parvovirus (PPV) is an important pathogen causing reproductive disorders in first
pregnant sows. The non-structure protein NS1 of PPV is a multifunctional protein playing a …