[HTML][HTML] Role of myokines in regulating skeletal muscle mass and function

JH Lee, HS Jun - Frontiers in physiology, 2019 - frontiersin.org
Loss of skeletal muscle mass and strength has recently become a hot research topic with the
extension of life span and an increasingly sedentary lifestyle in modern society …

Skeletal muscle fibrosis: an overview

MAA Mahdy - Cell and tissue research, 2019 - Springer
Extracellular matrix (ECM) is an essential component of skeletal muscle. It provides a
framework structure that holds myofibers and blood capillaries and nerves supplying the …

Congenital myopathies: disorders of excitation–contraction coupling and muscle contraction

H Jungbluth, S Treves, F Zorzato, A Sarkozy… - Nature Reviews …, 2018 - nature.com
The congenital myopathies are a group of early-onset, non-dystrophic neuromuscular
conditions with characteristic muscle biopsy findings, variable severity and a stable or slowly …

Muscle-to-tumor crosstalk: The effect of exercise-induced myokine on cancer progression

Q Huang, M Wu, X Wu, Y Zhang, Y Xia - Biochimica et Biophysica Acta …, 2022 - Elsevier
Physical exercise has gradually become a focus in cancer treatment due to its pronounced
role in reducing cancer risk, enhancing therapeutic efficacy, and improving prognosis. In …

ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension

LM Yung, P Yang, S Joshi, ZM Augur… - Science translational …, 2020 - science.org
Human genetics, biomarker, and animal studies implicate loss of function in bone
morphogenetic protein (BMP) signaling and maladaptive transforming growth factor–β …

Skeletal muscle is an endocrine organ

K Iizuka, T Machida, M Hirafuji - Journal of pharmacological sciences, 2014 - jstage.jst.go.jp
Skeletal muscle plays a key role in postural retention as well as locomotion for maintaining
the physical activities of human life. Skeletal muscle has a second role as an elaborate …

Muscle and cardiac therapeutic strategies for Duchenne muscular dystrophy: past, present, and future

A Łoboda, J Dulak - Pharmacological Reports, 2020 - Springer
Background Duchenne muscular dystrophy (DMD) is a severe X-linked neuromuscular
childhood disorder that causes progressive muscle weakness and degeneration and results …

Treating pediatric neuromuscular disorders: the future is now

JJ Dowling, H D. Gonorazky, RD Cohn… - American Journal of …, 2018 - Wiley Online Library
Pediatric neuromuscular diseases encompass all disorders with onset in childhood and
where the primary area of pathology is in the peripheral nervous system. These conditions …

[HTML][HTML] Interaction between sarcopenia and nonalcoholic fatty liver disease

SK Joo, W Kim - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Sarcopenia and nonalcoholic fatty liver disease (NAFLD) are common health problems
related to aging. Despite the differences in their diagnostic methods, several cross-sectional …

[HTML][HTML] Myostatin inhibitors as therapies for muscle wasting associated with cancer and other disorders

RC Smith, BK Lin - Current opinion in supportive and palliative …, 2013 - journals.lww.com
Myostatin inhibitors as therapies for muscle wasting associa... : Current Opinion in Supportive
and Palliative Care Myostatin inhibitors as therapies for muscle wasting associated with cancer …