The solute carrier family 16 (SLC16) is comprised of 14 members of the monocarboxylate
transporter (MCT) family that play an essential role in the transport of important cell nutrients …

Otto Warburg observed that cancerous cells prefer fermentative instead of oxidative
metabolism of glucose, although the former is in theory less efficient. Since Warburg's …

Sustaining and maintaining the intricate process of spermatogenesis is liable upon
hormones and growth factors acting through endocrine and paracrine pathways. The Sertoli …

Caffeine is a widely consumed substance present in several beverages. There is an
increasing consumption of energetic drinks, rich in caffeine, among young individuals in …

Elevated estradiol levels are correlated with male infertility. Causes of hyperestrogenism
include diseases of the adrenal cortex, testis or medications affecting the hypothalamus …

One of the hallmarks of cancer cells is the increased ability to acquire nutrients, particularly
glucose and glutamine. Proliferating cells need precursors for cell growth and NADPH …

Spermatogenesis is contingent upon hormones and growth factors acting through endocrine
and paracrine pathways either in vivo or in vitro. Sertoli cells (SCs) furnish essential factors …

Androgen receptor signaling pathway is necessary to complete spermatogenesis in testes.
Difference between androgen binding location in Sertoli cell classifies androgen receptor …

Diabetes mellitus (DM) is one of the most prevalent chronic diseases and has been a
leading cause of death in the last decades. Thus, methods to detect, prevent or delay this …

Background and Purpose M etformin is commonly used to treat type 2 diabetes (T2D). While
new clinical applications have been ascribed to metformin, including treatment of …