[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …
commercial point of view. In order to reach the systemic circulation after oral administration …
[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
Surface modification of lipid-based nanoparticles
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …
purposes, including the recent increase of these nanocarriers as vaccine components …
An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers
Oral administration is the most commonly used route for drug delivery owing to its cost-
effectiveness, ease of administration, and high patient compliance. However, the absorption …
effectiveness, ease of administration, and high patient compliance. However, the absorption …
Advances in oral absorption of polysaccharides: Mechanism, affecting factors, and improvement strategies
Z Zheng, X Pan, L Luo, Q Zhang, X Huang, Y Liu… - Carbohydrate …, 2022 - Elsevier
Polysaccharides have been widely used as biomaterials and drugs after oral administration
due to their suitable physicochemical properties, good bioactivities and low toxicities …
due to their suitable physicochemical properties, good bioactivities and low toxicities …
Potential of insulin nanoparticle formulations for oral delivery and diabetes treatment
CY Wong, H Al-Salami, CR Dass - Journal of controlled release, 2017 - Elsevier
Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …
Overcoming the intestinal barrier: a look into targeting approaches for improved oral drug delivery systems
Oral drug administration is one of the most preferred and simplest routes among both
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …
Lipid-based nanocarriers for oral peptide delivery
This article is aimed to overview the lipid-based nanostructures designed so far for the oral
administration of peptides and proteins, and to analyze the influence of their composition …
administration of peptides and proteins, and to analyze the influence of their composition …
Nanoparticle delivery systems in the treatment of diabetes complications
EB Souto, SB Souto, JR Campos, P Severino… - Molecules, 2019 - mdpi.com
Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …
[HTML][HTML] Advances in oral peptide drug nanoparticles for diabetes mellitus treatment
Y Li, W Zhang, R Zhao, X Zhang - Bioactive Materials, 2022 - Elsevier
Peptide drugs play an important role in diabetes mellitus treatment. Oral administration of
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …