Oxidative stress, a term that describes the imbalance between oxidants and antioxidants,
leads to the disruption of redox signals and causes molecular damage. Increased oxidative …

Peptic ulcers are characterized by erosions on the mucosa of the gastrointestinal tract that
may reach the muscle layer. Their etiology is multifactorial and occurs when the balance …

Background Kaempferol, a natural flavonoid, exhibits anticancer properties by scavenging
reactive oxygen species (ROS). However, increasing evidence has demonstrated that …

Diabetes mellitus (DM) is a group of metabolic disorders in which high blood sugar levels
occur over a prolonged period. Approximately 4% of the global population is affected by DM …

In this study, kaempferol (KFL) shows hepatoprotective activity against zearalenone (ZEA)-
induced oxidative stress and its underlying mechanisms in in vitro and in vivo models were …

Diabetic retinopathy (DR), a leading cause of vision loss and blindness worldwide, is
caused by retinal neurovascular unit dysfunction, and its cellular pathology involves at least …

The study aims to investigate whether kaemperfol (KAE) inhibits microglia pyroptosis and
subsequent neuroinflammatory response to exert neuroprotective effects, along with the …

Safflower (Carthamus tinctorius L.) is cultivated in various countries for the flavonoid
compounds it contains. These flavonoids have been used in many industries as drugs …

Diabetic retinopathy is a neurovascular complication of diabetes and the main cause of
vision loss in adults. Glial cells have a key role in maintenance of central nervous system …

Regulated cell death (RCD) guarantees to preserve organismal homeostasis. Apoptosis and
autophagy are two major arms of RCD, while endoplasmic reticulum (ER) as a crucial …