We read with great interest the systematic review on the use of botulinum toxin in treatment
of chronic anal fissure by Vitoopinyoparb et al.[1]. The study is interesting because it …

Background Chronic anal fissure is a common benign anorectal disease with a high
recurrence rate. Pelvic floor physical therapy has been proven effective in the short-term …

This longitudinal study aimed to assess the quality of life in patients with anal fissures
treated with botulinum toxin (Botox) injections over a one-year period. The study …

Methods Over a 10-year interval (2010–2019), patients with anal fissure who had previously
undergone lateral internal sphincterotomy were recruited for the study at the Fondazione …

Background It is unclear how patients with anal fissures are treated in real-world settings,
particularly since patients may not see colorectal surgeons. This study describes trends in …

During the 1970s, scientists first used botulinum toxin to treat strabismus. While testing on
monkeys, they noticed that the toxin could also reduce wrinkles in the glabella area. This led …

BACKGROUND Spastic pelvic floor syndrome (SPFS) is a refractory pelvic floor disease
characterized by abnormal (uncoordinated) contractions of the external anal sphincter and …

Background: Anal fistula is one of the most common diseases in anorectal surgery. The
wound healing after surgery can affect the prognosis of patients. We conducted a protocol …

Background: Anal fissure (AF) is the second most common anorectal complaint in healthcare
settings. The presentation might be acute or chronic, characterised by severe pain with …

Background: It is unclear how patients with anal fissures are treated in real-world settings,
particularly since patients may not see colorectal surgeons. This study describes trends in …