Stability and plasticity of regulatory T cells in health and disease

E Contreras-Castillo, VY García-Rasilla… - Journal of Leukocyte …, 2024 - academic.oup.com
The mechanisms that negatively regulate inflammation upon a pathogenic stimulus are
crucial for the maintenance of tissue integrity and organ function. T regulatory cells are one …

Epigenetic control of multiple genes with a lentiviral vector encoding transcriptional repressors fused to compact zinc finger arrays

D Monteferrario, M David, SK Tadi, Y Zhou… - … Therapy Methods & …, 2024 - cell.com
Gene silencing without gene editing holds great potential for the development of safe
therapeutic applications. Here, we describe a novel strategy to concomitantly repress …