Nitric oxide signaling in health and disease

JO Lundberg, E Weitzberg - Cell, 2022 - cell.com
The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

Nitric oxide: physiological functions, delivery, and biomedical applications

SM Andrabi, NS Sharma, A Karan… - Advanced …, 2023 - Wiley Online Library
Nitric oxide (NO) is a gaseous molecule that has a central role in signaling pathways
involved in numerous physiological processes (eg, vasodilation, neurotransmission …

Macrophage reprogramming and cancer therapeutics: role of iNOS-derived NO

K Kashfi, J Kannikal, N Nath - Cells, 2021 - mdpi.com
Nitric oxide and its production by iNOS is an established mechanism critical to tumor
promotion or suppression. Macrophages have important roles in immunity, development …

Clinical applications and anticancer effects of antimicrobial peptides: from bench to bedside

A Jafari, A Babajani, R Sarrami Forooshani… - Frontiers in …, 2022 - frontiersin.org
Cancer is a multifaceted global health issue and one of the leading causes of death
worldwide. In recent years, medical science has achieved great advances in the diagnosis …

NO donors as the wonder molecules with therapeutic potential: Recent trends and future perspectives

GR Navale, S Singh, K Ghosh - Coordination Chemistry Reviews, 2023 - Elsevier
Nitric oxide (NO), an endogenous, free radical, highly unstable, diatomic gaseous molecule,
plays crucial roles in several physiological and pathological processes. It has attracted …

The potential of L-arginine in prevention and treatment of disturbed carbohydrate and lipid metabolism—a review

A Szlas, JM Kurek, Z Krejpcio - Nutrients, 2022 - mdpi.com
L-arginine, an endogenous amino acid, is a safe substance that can be found in food. The
compound is involved in synthesis of various products responsible for regulatory functions in …

Regulation of pleiotropic physiological roles of nitric oxide signaling

L Soundararajan, A Dharmarajan, P Samji - Cellular signalling, 2023 - Elsevier
Nitric Oxide (NO) is a highly diffusible, ubiquitous signaling molecule and a free radical that
is naturally synthesized by our body. The pleiotropic effects of NO in biological systems are …

Nitric oxide as a central molecule in hypertension: Focus on the vasorelaxant activity of new nitric oxide donors

GM da Silva, MC da Silva, DVG Nascimento… - Biology, 2021 - mdpi.com
Simple Summary Nitric oxide is an important molecule that performs a variety of functions in
our bodies, especially in the cardiovascular system. In certain pathological conditions, such …

Nitric oxide-driven nanotherapeutics for cancer treatment

Z Zhao, X Shan, H Zhang, X Shi, P Huang, J Sun… - Journal of Controlled …, 2023 - Elsevier
Nitric oxide (NO) is a gaseous molecule endowed with diverse biological functions, offering
vast potential in the realm of cancer treatment. Considerable efforts have been dedicated to …

Argon gas plasma-treated physiological solutions stimulate immunogenic cell death and eradicates immunosuppressive CD47 protein in lung carcinoma

M Negi, N Kaushik, LN Nguyen, EH Choi… - Free Radical Biology and …, 2023 - Elsevier
Cold atmospheric plasma-treated liquids (PTLs) exhibit selective toxicity toward tumor cells
and are provoked by a cocktail of reactive oxygen and nitrogen species in such liquids …