Metabolic syndrome: updates on pathophysiology and management in 2021

G Fahed, L Aoun, M Bou Zerdan, S Allam… - International journal of …, 2022 - mdpi.com
Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

[HTML][HTML] Cellular Red-Ox system in health and disease: The latest update

AB Jena, RR Samal, NK Bhol, AK Duttaroy - Biomedicine & …, 2023 - Elsevier
Cells are continually exposed to reactive oxygen species (ROS) generated during cellular
metabolism. Apoptosis, necrosis, and autophagy are biological processes involving a …

Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF‐κB Suppression and NLRP3 …

Y Ran, W Su, F Gao, Z Ding, S Yang… - Oxidative medicine …, 2021 - Wiley Online Library
NLRP3 inflammasome‐mediated pyroptosis is a proinflammatory programmed cell death
pathway, which plays a vital role in functional outcomes after stroke. We previously …

Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects

AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

Oral colon-targeted mucoadhesive micelles with enzyme-responsive controlled release of curcumin for ulcerative colitis therapy

C Zhang, J Li, M Xiao, D Wang, Y Qu, L Zou… - Chinese Chemical …, 2022 - Elsevier
Although multitudinous nanoscale drug-delivery systems (DDSs) have been recommended
to improve anti-ulcerative colitis (UC) outcomes, to enhance the mucoadhesion of …

Pyroptosis, a new bridge to tumor immunity

L Li, M Jiang, L Qi, Y Wu, D Song, J Gan, Y Li… - Cancer …, 2021 - Wiley Online Library
Pyroptosis refers to the process of gasdermin (GSDM)‐mediated programmed cell death
(PCD). Our understanding of pyroptosis has expanded beyond cells and is known to involve …

The role of curcumin in cancer treatment

V Zoi, V Galani, GD Lianos, S Voulgaris, AP Kyritsis… - Biomedicines, 2021 - mdpi.com
Curcumin is a polyphenol extracted from the rhizomes of the turmeric plant, Curcuma longa
which has anti-inflammatory, and anticancer properties. Chronic inflammation is associated …

Curcumin, a traditional spice component, can hold the promise against COVID-19?

VK Soni, A Mehta, YK Ratre, AK Tiwari, A Amit… - European Journal of …, 2020 - Elsevier
The severity of the recent pandemic and the absence of any specific medication impelled the
identification of existing drugs with potential in the treatment of Coronavirus disease-2019 …

The beneficial therapeutic effects of plant‐derived natural products for the treatment of sarcopenia

M Bagherniya, A Mahdavi… - Journal of Cachexia …, 2022 - Wiley Online Library
Sarcopenia is an age‐related muscle disorder typically associated with a poor quality of life.
Its definition has evolved over time, and several underlying causes of sarcopenia in the …

[HTML][HTML] A review of the potential use of pinene and linalool as terpene-based medicines for brain health: discovering novel therapeutics in the flavours and fragrances …

K Weston-Green, H Clunas… - Frontiers in psychiatry, 2021 - frontiersin.org
“Medicinal cannabis” is defined as the use of cannabis-based products for the treatment of
an illness. Investigations of cannabis compounds in psychiatric and neurological illnesses …