Common mechanisms underlying diabetic vascular complications: focus on the interaction of metabolic disorders, immuno-inflammation, and endothelial dysfunction

C Xue, K Chen, Z Gao, T Bao, LS Dong, L Zhao… - Cell Communication and …, 2023 - Springer
Diabetic vascular complications (DVCs), including macro-and micro-angiopathy, account for
a high percentage of mortality in patients with diabetes mellitus (DM). Endothelial …

Natural products in attenuating renal inflammation via inhibiting the NLRP3 inflammasome in diabetic kidney disease

Y Wang, Z Sui, M Wang, P Liu - Frontiers in Immunology, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is a prevalent and severe complications of diabetes and
serves as the primary cause of end-stage kidney disease (ESKD) globally. Increasing …

Lupenone improves type 2 diabetic nephropathy by regulating NF-κB pathway-mediated inflammation and TGF-β1/Smad/CTGF-associated fibrosis

H Wu, F Xu, X Huang, X Li, P Yu, L Zhang, X Yang… - Phytomedicine, 2023 - Elsevier
Background Type 2 diabetic nephropathy is a common diabetic complication and the main
cause of death in patients with diabetes. Research has aimed to find an ideal drug with …

Mulberry leaf extract and neochlorogenic acid ameliorate glucolipotoxicity-induced diabetic nephropathy in high-fat diet-fed db/db mice

TW Hung, MY Yang, MH Yu, IN Tsai, YC Tsai… - Food & Function, 2023 - pubs.rsc.org
Diabetic nephropathy, a major diabetes complication, is often exacerbated by
glucolipotoxicity. The potential benefits of mulberry leaf extract (MLE) and its primary …

[PDF][PDF] Essential Oil of Satureja montana L. from Herzegovina: Assessment of Composition, Antispasmodic, and Antidiarrheal Effects.

M Kulić, D Drakul, D Sokolović… - Records of Natural …, 2023 - acgpubs.org
Satureja montana L.(SM) has a long traditional use as a spice and a medicine for various
gastrointestinal disorders, including painful spasms and diarrhea. Contrary to conventional …

Association between a high triglyceride–glucose index and chronic kidney disease in adult patients with latent autoimmune diabetes

X Fu, Z Xu, Q Tan, W Wei, Z Wang - BMC Endocrine Disorders, 2023 - Springer
Background Insulin resistance (IR) is one of the risk factors for chronic kidney disease (CKD)
and diabetes. The triglyceride–glucose (TyG) index is considered a reliable alternative …

MAGI2 ameliorates podocyte apoptosis of diabetic kidney disease through communication with TGF‐β‐Smad3/nephrin pathway

T Wang, C Li, X Wang, F Liu - The FASEB Journal, 2023 - Wiley Online Library
Podocytes, the key component of the glomerular filtration barrier (GFB), are gradually lost
during the progression of diabetic kidney disease (DKD), severely compromising kidney …

Iridoids modulate inflammation in diabetic kidney disease: A review

T Zhou, N Tian, L Li, R Yu - Journal of Integrative Medicine, 2024 - Elsevier
In recent years, preclinical research on diabetic kidney disease (DKD) has surged to the
forefront of scientific and clinical attention. DKD has become a pervasive complication of …

[HTML][HTML] Fibroblast growth factor 21 mitigates lupus nephritis progression via the FGF21/Irgm 1/NLRP3 inflammasome pathway

Y Zou, D Wang, W Sun, Q Wu, S Liu, Z Ren, Y Li… - International …, 2024 - Elsevier
As an endocrine cytokine, fibroblast growth factor 21 (FGF21) exhibits anti-inflammatory
properties. With the development of lupus nephritis (LN), which is tightly related to …

[HTML][HTML] Molecular Mechanisms and Therapeutic Potential of Natural Flavonoids in Diabetic Nephropathy: Modulation of Intracellular Developmental Signaling …

MK Sulaiman - Current Research in Pharmacology and Drug …, 2024 - Elsevier
Recognized as a common microvascular complication of diabetes mellitus (DM), diabetic
nephropathy (DN) is the principal cause of chronic end-stage renal disease (ESRD) …