Chronic wounds are a health problem that have devastating consequences for patients and
contribute major costs to healthcare systems and societies. To understand the magnitude of …

Neutrophils promptly accumulate in large numbers at sites of tissue injury. Injuries to the skin
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …

Guideline Summary Chronic limb-threatening ischemia (CLTI) is associated with mortality,
amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are …

Objective The aim of this study was to determine the cost of chronic wound care for Medicare
beneficiaries in aggregate, by wound type and by setting. Methods This retrospective …

There may be significant deficiencies in the knowledge among nurses, 38–40 an issue
recognised by many. 41 A survey of community nurses in Ireland found that more than half …

Introduction Fibromyalgia (FM) is a common disorder characterised by heterogeneous
symptoms often leading to decreased functioning, work productivity and quality of life …

Diabetic wounds are recalcitrant to healing. However, the mechanism causing this
dysfunction is not fully understood. High expression of matrix metalloproteinase-9 (MMP-9) …

Introduction: Chronic, nonhealing skin wounds claim> 3% of the health-care budget in
industrialized countries, and the incidence is rising. Currently, two parallel trends influence …

Wound healing is a complex process with a linear development that involves many actors in
a multistep timeline commonly divided into four stages: Hemostasis, inflammation …

The number of people in the world with diabetes has nearly quadrupled in the past 40 years.
Current data show that 25% of these diabetics will develop a foot ulcer in their lifetime and …