[HTML][HTML] Regulated cell death (RCD) in cancer: key pathways and targeted therapies
F Peng, M Liao, R Qin, S Zhu, C Peng, L Fu… - Signal transduction and …, 2022 - nature.com
Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …
form of cell death that can be regulated by a variety of biomacromolecules, which is …
[HTML][HTML] MAPK/ERK signaling pathway in hepatocellular carcinoma
H Moon, SW Ro - Cancers, 2021 - mdpi.com
Simple Summary The mitogen-activated protein kinase/extracellular signal-regulated kinase
(MAPK/ERK) signaling pathway is frequently activated in liver cancer, which is one of the …
(MAPK/ERK) signaling pathway is frequently activated in liver cancer, which is one of the …
Highly retina-permeating and long-acting resveratrol/metformin nanotherapeutics for enhanced treatment of macular degeneration
The development of therapeutics for effective treatments of retinal diseases is significantly
constrained by various biological barriers. We herein report a nanomedicine strategy to …
constrained by various biological barriers. We herein report a nanomedicine strategy to …
Cellular aging beyond cellular senescence: Markers of senescence prior to cell cycle arrest in vitro and in vivo
M Ogrodnik - Aging cell, 2021 - Wiley Online Library
The field of research on cellular senescence experienced a rapid expansion from being
primarily focused on in vitro aspects of aging to the vast territories of animal and clinical …
primarily focused on in vitro aspects of aging to the vast territories of animal and clinical …
[HTML][HTML] The role of oxidative stress in ovarian aging: a review
F Yan, Q Zhao, Y Li, Z Zheng, X Kong, C Shu… - Journal of ovarian …, 2022 - Springer
Ovarian aging refers to the process by which ovarian function declines until eventual failure.
The pathogenesis of ovarian aging is complex and diverse; oxidative stress (OS) is …
The pathogenesis of ovarian aging is complex and diverse; oxidative stress (OS) is …
The angiotensin AT2 receptor: from a binding site to a novel therapeutic target
UM Steckelings, RE Widdop, ED Sturrock… - Pharmacological …, 2022 - ASPET
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from
a binding site with unknown function to a firmly established major effector within the …
a binding site with unknown function to a firmly established major effector within the …
Apoptosis in Alzheimer's disease: insight into the signaling pathways and therapeutic avenues
S Kumari, R Dhapola, DHK Reddy - Apoptosis, 2023 - Springer
Alzheimer's disease (AD) is characterized by the accumulation of hyperphosphorylated tau
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …
[HTML][HTML] Anticancer activity of propolis and its compounds
E Forma, M Bryś - Nutrients, 2021 - mdpi.com
Propolis is a natural material that honey bees (Apis mellifera) produce from various
botanical sources. The therapeutic activity of propolis, including antibacterial, antifungal, and …
botanical sources. The therapeutic activity of propolis, including antibacterial, antifungal, and …
The signaling pathways and targets of traditional Chinese medicine and natural medicine in triple-negative breast cancer
Z Yang, Q Zhang, L Yu, J Zhu, Y Cao, X Gao - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Triple-negative breast cancer (TNBC) has a poorer
prognosis than other subtypes due to its strong invasion and higher risk of distant …
prognosis than other subtypes due to its strong invasion and higher risk of distant …
Mechanically reinforced injectable bioactive nanocomposite hydrogels for in-situ bone regeneration
Gelatin-methacryloyl (GelMA) has received extensive attention in tissue engineering
because of its low antigenicity, suitable biodegradability, and similarity to ECM. However, it …
because of its low antigenicity, suitable biodegradability, and similarity to ECM. However, it …