Advances in antitumor activity and mechanism of natural steroidal saponins: A review of advances, challenges, and future prospects

F Wang, L Liang, M Yu, W Wang, IH Badar, Y Bao… - Phytomedicine, 2024 - Elsevier
Background Cancer, the second leading cause of death worldwide following cardiovascular
diseases, presents a formidable challenge in clinical settings due to the extensive toxic side …

[HTML][HTML] Pyrotinib combined with vinorelbine in patients with previously treated HER2-positive metastatic breast cancer: a multicenter, single-arm, prospective study

K Jiang, R Hong, W Xia, Q Lu, L Li… - Cancer Research and …, 2024 - ncbi.nlm.nih.gov
Purpose This study aims to evaluate the efficacy and safety of a new combination treatment
of vinorelbine and pyrotinib in human epidermal growth factor receptor 2 (HER2)–positive …

Patient-derived xenografts as an innovative surrogate tumor model for the investigation of health disparities in triple negative breast cancer

MD Matossian, AA Giardina, MK Wright… - Women's Health …, 2020 - liebertpub.com
Despite a decline in overall incidence rates for cancer in the past decade, due in part to
impressive advancements in both diagnosis and treatment, breast cancer (BC) remains the …

长春瑞滨药动学及毒副作用研究进展

刘花, 陈延绅, 尤慧柠, 冯燕, 李敏, 寇建蓉… - 中国 …, 2022 - journal.china-pharmacy.com
长春瑞滨(NVB) 是一种半合成的长春花生物碱, 可通过抑制微管蛋白的合成而发挥抗肿瘤作用,
因其口服制剂服用方便且具有良好的临床疗效, 目前已应用于多种肿瘤的治疗. NVB …

[HTML][HTML] Кардиотоксические эффекты алкалоидов тисового дерева и барвинка розового

ГС Маль, ЕБ Артюшкова, МП Гладченко… - Безопасность и риск …, 2021 - cyberleninka.ru
Противоопухолевые препараты растительного происхождения на основе алкалоидов
барвинка розового и тисового дерева включены в схемы комплексной терапии многих …

Cardiotoxic Effects of Yew Tree and Pink Periwinkle Alkaloids

GS Mal, EB Artyushkova, MP Gladchenko… - Safety and Risk of …, 2021 - risksafety.ru
Antitumour herbal medicines based on pink periwinkle and yew tree alkaloids are included
in combination therapies for many types of cancer. The use of these classes of products may …

Tratamiento del cáncer de mama metastásico con HER2+ con vinorelbina oral y bloqueo dual con Pertuzumab y Trastuzumab

L Valiente Gómez - 2020 - repositorio.unican.es
Approximately 20% of breast carcinomas are 'HER2 positive': they behave aggressive by
overexpression of HER2 membrane protein, in turn by amplification of c-erbB2 encoding …