Individual‐level brain morphological similarity networks: Current methodologies and applications

M Cai, J Ma, Z Wang, Y Zhao, Y Zhang… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims The human brain is an extremely complex system in which neurons, clusters of
neurons, or regions are connected to form a complex network. With the development of …

Toward individualized connectomes of brain morphology

J Wang, Y He - Trends in Neurosciences, 2024 - cell.com
The morphological brain connectome (MBC) delineates the coordinated patterns of local
morphological features (such as cortical thickness) across brain regions. While classically …

Four distinct subtypes of Alzheimer's disease based on resting-state connectivity biomarkers

P Chen, H Yao, BM Tijms, P Wang, D Wang, C Song… - Biological …, 2023 - Elsevier
Background Alzheimer's disease (AD) is a neurodegenerative disorder with significant
heterogeneity. Different AD phenotypes may be associated with specific brain network …

Edge-centric effective connection network based on muti-modal MRI for the diagnosis of Alzheimer's disease

S Zhang, H Zhao, W Wang, Z Wang, X Luo, A Hramov… - Neurocomputing, 2023 - Elsevier
Alzheimer's disease (AD) is an irreversible neurodegenerative disease. But if AD is detected
early, it can greatly reduce the severity of the disease. Functional connection networks …

A neuroimaging biomarker for Individual Brain-Related Abnormalities In Neurodegeneration (IBRAIN): a cross-sectional study

K Zhao, P Chen, A Alexander-Bloch, Y Wei… - …, 2023 - thelancet.com
Background Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that poses
a worldwide public health challenge. A neuroimaging biomarker would significantly improve …

Morphological connectivity differences in Alzheimer's disease correlate with gene transcription and cell‐type

H Yu, Y Ding, Y Wei, M Dyrba, D Wang… - Human brain …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the most prevalent forms of dementia in older individuals.
Convergent evidence suggests structural connectome abnormalities in specific brain …

A comprehensive characterization of hippocampal feature ensemble serves as individualized brain signature for Alzheimer's disease: deep learning analysis in 3238 …

Y Zhang, H Li, Q Zheng - European Radiology, 2023 - Springer
Objectives Hippocampal characterization is one of the most significant hallmarks of
Alzheimer's disease (AD); rather, the single-level feature is insufficient. A comprehensive …

Identifying Alzheimer's disease and mild cognitive impairment with atlas-based multi-modal metrics

Z Long, J Li, J Fan, B Li, Y Du, S Qiu, J Miao… - Frontiers in Aging …, 2023 - frontiersin.org
Introduction Multi-modal neuroimaging metrics in combination with advanced machine
learning techniques have attracted more and more attention for an effective multi-class …

Robustly uncovering the heterogeneity of neurodegenerative disease by using data-driven subtyping in neuroimaging: A review

P Chen, S Zhang, K Zhao, X Kang, T Rittman, Y Liu - Brain Research, 2023 - Elsevier
Neurodegenerative diseases are associated with heterogeneity in genetics, pathology, and
clinical manifestation. Understanding this heterogeneity is particularly relevant for clinical …

Altered large‐scale dynamic connectivity patterns in Alzheimer's disease and mild cognitive impairment patients: A machine learning study

R Jing, P Chen, Y Wei, J Si, Y Zhou… - Human Brain …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a common neurodegeneration disease associated with
substantial disruptions in the brain network. However, most studies investigated static …