Protein glycosylation in cancer

SR Stowell, T Ju, RD Cummings - Annual Review of Pathology …, 2015 - annualreviews.org
Neoplastic transformation results in a wide variety of cellular alterations that impact the
growth, survival, and general behavior of affected tissue. Although genetic alterations …

The involvement of exosomes in the diagnosis and treatment of pancreatic cancer

AN Ariston Gabriel, F Wang, Q Jiao, U Yvette, X Yang… - Molecular cancer, 2020 - Springer
At the moment, pancreatic cancer is among the deadliest gastrointestinal diseases, and
pancreatic cancer growth is a complex biological process that is based on different kinds of …

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

SA Melo, LB Luecke, C Kahlert, AF Fernandez… - Nature, 2015 - nature.com
Exosomes are lipid-bilayer-enclosed extracellular vesicles that contain proteins and nucleic
acids. They are secreted by all cells and circulate in the blood. Specific detection and …

Nanoplasmonic quantification of tumour-derived extracellular vesicles in plasma microsamples for diagnosis and treatment monitoring

K Liang, F Liu, J Fan, D Sun, C Liu, CJ Lyon… - Nature biomedical …, 2017 - nature.com
Tumour-derived extracellular vesicles (EVs) are of increasing interest as a resource of
diagnostic biomarkers. However, most EV assays require large samples and are time …

The bioengineered and multifunctional nanoparticles in pancreatic cancer therapy: Bioresponisive nanostructures, phototherapy and targeted drug delivery

MJ Saadh, H Baher, Y Li, JL Arias-Gonzáles… - Environmental …, 2023 - Elsevier
The multidisciplinary approaches in treatment of cancer appear to be essential in term of
bringing benefits of several disciplines and their coordination in tumor elimination. Because …

LncRNA co-expression network analysis reveals novel biomarkers for pancreatic cancer

M Giulietti, A Righetti, G Principato, F Piva - Carcinogenesis, 2018 - academic.oup.com
High mortality and low survival rates for pancreatic ductal adenocarcinoma (PDAC) mainly
result from the delay in diagnosis and treatment. Therefore, there is an urgent need to …

[HTML][HTML] Prognostic and predictive markers in pancreatic adenocarcinoma

N Le, M Sund, A Vinci, G Beyer, MA Javed… - Digestive and Liver …, 2016 - Elsevier
Pancreatic ductal adenocarcinoma is characterized by a poor prognosis and a low median
survival, despite improvements observed for many other solid tumours. Intensive research …

Salivary analysis: An emerging paradigm for non‐invasive healthcare diagnosis and monitoring

C Liao, X Chen, Y Fu - Interdisciplinary Medicine, 2023 - Wiley Online Library
As an emerging non‐invasive and easy‐to‐use toolkit, salivary analysis has garnered
significant attention recently. By leveraging the latest discoveries in salivary biomarkers …

Serum lactate dehydrogenase predicts prognosis and correlates with systemic inflammatory response in patients with advanced pancreatic cancer after gemcitabine …

SL Yu, LT Xu, Q Qi, YW Geng, H Chen, ZQ Meng… - Scientific reports, 2017 - nature.com
Serum lactate dehydrogenase (LDH) concentrations correlate with tumor progression and
poor outcome. We evaluated the predictive value of serum LDH level for overall survival …

Identification and prognostic analysis of biomarkers to predict the progression of pancreatic cancer patients

W Li, T Li, C Sun, Y Du, L Chen, C Du, J Shi… - Molecular Medicine, 2022 - Springer
Background Pancreatic cancer (PC) is a malignancy with a poor prognosis and high
mortality. Surgical resection is the only “curative” treatment. However, only a minority of …