[HTML][HTML] Epidemiology of glioblastoma multiforme–literature review

S Grochans, AM Cybulska, D Simińska, J Korbecki… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) is one of the most aggressive
malignancies, accounting for 14.5% of all central nervous system tumors and 48.6% of …

[HTML][HTML] The hypoxia-driven crosstalk between tumor and tumor-associated macrophages: mechanisms and clinical treatment strategies

R Bai, Y Li, L Jian, Y Yang, L Zhao, M Wei - Molecular Cancer, 2022 - Springer
Given that hypoxia is a persistent physiological feature of many different solid tumors and a
key driver for cancer malignancy, it is thought to be a major target in cancer treatment …

[HTML][HTML] The immunological impact of IL-1 family cytokines on the epidermal barrier

T Macleod, A Berekmeri, C Bridgewood… - Frontiers in …, 2021 - frontiersin.org
The skin barrier would not function without IL-1 family members, but their physiological role
in the immunological aspects of skin barrier function are often overlooked. This review …

[HTML][HTML] Harnessing Pyroptosis for Cancer Immunotherapy

CM Bourne, CY Taabazuing - Cells, 2024 - mdpi.com
Cancer immunotherapy is a novel pillar of cancer treatment that harnesses the immune
system to fight tumors and generally results in robust antitumor immunity. Although …

[HTML][HTML] The three-dimensional in vitro cell culture models in the study of oral cancer immune microenvironment

E Dalir Abdolahinia, X Han - Cancers, 2023 - mdpi.com
Simple Summary The extensive array of applications in 3D culture models closely mimics
the precise physiological conditions of in vivo settings, enabling the investigation of …

Immune suppressive function of IL-1α release in the tumor microenvironment regulated by calpain 1

D Lin, Y Mei, L Lei, Z Binte Hanafi, Z Jin, Y Liu… - …, 2022 - Taylor & Francis
ABSTRACT Interleukin-1α (IL-1α) plays an important role in inflammation and
hematopoiesis. Many tumors have increased IL-1α expression. However, the immune …

[HTML][HTML] Innate-immunity genes in obesity

SV Mikhailova, DE Ivanoshchuk - Journal of personalized medicine, 2021 - mdpi.com
The main functions of adipose tissue are thought to be storage and mobilization of the
body's energy reserves, active and passive thermoregulation, participation in the spatial …

[HTML][HTML] miR-142: A Master Regulator in Hematological Malignancies and Therapeutic Opportunities

W Huang, D Paul, GA Calin, R Bayraktar - Cells, 2023 - mdpi.com
MicroRNAs (miRNAs) are a type of non-coding RNA whose dysregulation is frequently
associated with the onset and progression of human cancers. miR-142, an ultra-conserved …

Cancer cells promote immune regulatory function of macrophages by upregulating scavenger receptor MARCO expression

C Gu, M Wiest, W Zhang, K Halder… - The Journal of …, 2023 - journals.aai.org
Expression of macrophage receptor with collagenous structure (MARCO) by tumor-
associated macrophages is associated with poor prognosis of multiple types of cancer. In …

Screening the critical protein subnetwork to delineate potential mechanisms and protective agents associated with arsenic-induced cutaneous squamous cell …

M Koushki, N Amiri-Dashatan… - Food and Chemical …, 2024 - Elsevier
Recent studies show that complex mechanisms are involved in arsenic-induced malignant
transformation of cells. This study aimed to decipher molecular mechanisms associated with …