[HTML][HTML] Phytocannabinoids: origins and biosynthesis

T Gülck, BL Møller - Trends in plant science, 2020 - cell.com
Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …

Natural products: an evolving role in future drug discovery

BB Mishra, VK Tiwari - European journal of medicinal chemistry, 2011 - Elsevier
The therapeutic areas of infectious diseases and oncology have benefited from abundant
scaffold diversity in natural products, able to interact with many specific targets within the cell …

An insight into anticancer effect of propolis and its constituents: a review of molecular mechanisms

P Elumalai, N Muninathan… - Evidence‐Based …, 2022 - Wiley Online Library
Propolis is a natural compound collected by honeybees from different parts of plants.
Honeybees produce a sticky component besides honey by mixing the tree resin and other …

Chemical elicitors versus secondary metabolite production in vitro using plant cell, tissue and organ cultures: recent trends and a sky eye view appraisal

CC Giri, M Zaheer - Plant Cell, Tissue and Organ Culture (PCTOC), 2016 - Springer
Plant secondary biosynthetic pathways are exceedingly inducible by elicitors and facilitate
enhanced metabolite production using plant cell tissue and organ cultures. Elicitors can …

The relevance of higher plants in lead compound discovery programs

AD Kinghorn, L Pan, JN Fletcher… - Journal of natural …, 2011 - ACS Publications
Along with compounds from terrestrial microorganisms, the constituents of higher plants
have provided a substantial number of the natural product-derived drugs used currently in …

[HTML][HTML] Membrane interactions of phytochemicals as their molecular mechanism applicable to the discovery of drug leads from plants

H Tsuchiya - Molecules, 2015 - mdpi.com
In addition to interacting with functional proteins such as receptors, ion channels, and
enzymes, a variety of drugs mechanistically act on membrane lipids to change the …

Synthesis and in vitro evaluation of novel coumarin–chalcone hybrids as potential anticancer agents

KV Sashidhara, A Kumar, M Kumar, J Sarkar… - Bioorganic & medicinal …, 2010 - Elsevier
A series of coumarin–chalcone hybrids have been synthesized and evaluated for their in
vitro cytotoxicity against a panel of four human cancer cell lines and normal fibroblasts …

Muscarine, imidazole, oxazole, and thiazole alkaloids

Z Jin - Natural product reports, 2011 - pubs.rsc.org
Covering: July 2007 to June 2010. Previous review: Nat. Prod. Rep., 2009, 26, 382–445 A
great number of structurally diverse natural products containing five-membered heterocyclic …

The saponins–polar isoprenoids with important and diverse biological activities

A Osbourn, RJM Goss, RA Field - Natural product reports, 2011 - pubs.rsc.org
Covering: up to the end of 2010 Saponins are polar molecules that consist of a triterpene or
steroid aglycone with one or more sugar chains. They are one of the most numerous and …

Neuroprotective effects of anthocyanin-and proanthocyanidin-rich extracts in cellular models of Parkinson׳ s disease

KE Strathearn, GG Yousef, MH Grace, SL Roy… - Brain research, 2014 - Elsevier
Neuropathological evidence indicates that dopaminergic cell death in Parkinson׳ s disease
(PD) involves impairment of mitochondrial complex I, oxidative stress, microglial activation …