The relationship between the right ventricle and its load in pulmonary hypertension

A Vonk Noordegraaf, BE Westerhof… - Journal of the American …, 2017 - jacc.org
In pulmonary hypertension, the right ventricle adapts to the increasing vascular load by
enhancing contractility (“coupling”) to maintain flow. Ventriculoarterial coupling implies that …

Evaluation and management of pulmonary hypertension in noncardiac surgery: a scientific statement from the American Heart Association

S Rajagopal, K Ruetzler, K Ghadimi, EM Horn… - Circulation, 2023 - Am Heart Assoc
Pulmonary hypertension, defined as an elevation in blood pressure in the pulmonary
arteries, is associated with an increased risk of death. The prevalence of pulmonary …

Pathobiology of pulmonary arterial hypertension and right ventricular failure

NF Voelkel, J Gomez-Arroyo, A Abbate… - European …, 2012 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is no longer an orphan disease. There are three
different classes of drugs for the treatment of PAH that are currently being used and an …

The right ventricle and pulmonary hypertension

MC van de Veerdonk, HJ Bogaard, NF Voelkel - Heart failure reviews, 2016 - Springer
In patients with pulmonary hypertension (PH), the primary cause of death is right ventricular
(RV) failure. Improvement in RV function is therefore one of the most important treatment …

The use of multimodality cardiovascular imaging to assess right ventricular size and function

E Surkova, D Muraru, S Iliceto, LP Badano - International journal of …, 2016 - Elsevier
Right ventricular (RV) size and function have been found to be important predictors of
cardiovascular morbidity and mortality in patients with various conditions. However, non …

[HTML][HTML] Mechanics of right ventricular dysfunction in pulmonary arterial hypertension and heart failure with preserved ejection fraction

RJ Bernardo, F Haddad, EJ Couture… - Cardiovascular …, 2020 - ncbi.nlm.nih.gov
Right ventricular (RV) dysfunction is the most important determinant of survival in patients
with pulmonary hypertension (PH). The manifestations of RV dysfunction not only include …

Treatment strategies for the right heart in pulmonary hypertension

BE Westerhof, N Saouti… - Cardiovascular …, 2017 - academic.oup.com
The function of the right ventricle (RV) determines the prognosis of patients with pulmonary
hypertension. While much progress has been made in the treatment of pulmonary …

Methods for measuring right ventricular function and hemodynamic coupling with the pulmonary vasculature

A Bellofiore, NC Chesler - Annals of biomedical engineering, 2013 - Springer
The right ventricle (RV) is a pulsatile pump, the efficiency of which depends on proper
hemodynamic coupling with the compliant pulmonary circulation. The RV and pulmonary …

Right ventricular failure due to chronic pressure load: What have we learned in animal models since the NIH working group statement?

MAJ Borgdorff, MG Dickinson, RMF Berger… - Heart failure …, 2015 - Springer
Right ventricular (RV) failure determines outcome in patients with pulmonary hypertension,
congenital heart diseases and in left ventricular failure. In 2006, the Working Group on …

Fasting 2-Deoxy-2-[18F]fluoro-d-glucose Positron Emission Tomography to Detect Metabolic Changes in Pulmonary Arterial Hypertension Hearts over 1 Year

EL Lundgrin, MM Park, J Sharp, WHW Tang… - Annals of the …, 2013 - atsjournals.org
Background: The development of tools to monitor the right ventricle in pulmonary arterial
hypertension (PAH) is of clinical importance. PAH is associated with pathologic expression …