Recent advances on gelatin methacrylate hydrogels with controlled microstructures for tissue engineering

Y Zhang, H Chen, J Li - International Journal of Biological Macromolecules, 2022 - Elsevier
Hydrogels with high water content and porous structures are excellent 3D scaffolds for
various applications in tissue engineering. Gelatin methacryloyl (GelMA) hydrogels with cell …

Gelatin methacryloyl hydrogel, from standardization, performance, to biomedical application

J He, Y Sun, Q Gao, C He, K Yao… - Advanced …, 2023 - Wiley Online Library
Gelatin methacryloyl (GelMA), a photocurable hydrogel, is widely used in 3D culture,
particularly in 3D bioprinting, due to its high biocompatibility, tunable physicochemical …

[HTML][HTML] In vitro biomimetic models for glioblastoma-a promising tool for drug response studies

T Stanković, T Ranđelović, M Dragoj, SS Burić… - Drug Resistance …, 2021 - Elsevier
The poor response of glioblastoma to current treatment protocols is a consequence of its
intrinsic drug resistance. Resistance to chemotherapy is primarily associated with …

Drug screening of human GBM spheroids in brain cancer chip

M Akay, J Hite, NG Avci, Y Fan, Y Akay, G Lu, JJ Zhu - Scientific reports, 2018 - nature.com
Glioblastoma multiforme (GBM), an extremely invasive and high-grade (grade IV) glioma, is
the most common and aggressive form of brain cancer. It has a poor prognosis, with a …

Perivascular signals alter global gene expression profile of glioblastoma and response to temozolomide in a gelatin hydrogel

MT Ngo, BAC Harley - Biomaterials, 2019 - Elsevier
Glioblastoma (GBM) is the most common primary malignant brain tumor, with patients
exhibiting poor survival (median survival time: 15 months). Difficulties in treating GBM …

The influence of hyaluronic acid and glioblastoma cell coculture on the formation of endothelial cell networks in gelatin hydrogels

MT Ngo, BA Harley - Advanced healthcare materials, 2017 - Wiley Online Library
Glioblastoma (GBM) is the most common and deadly form of brain cancer. Interactions
between GBM cells and vasculature in vivo contribute to poor clinical outcomes, with GBM …

Developing a biomimetic tooth bud model

EE Smith, W Zhang, NR Schiele… - Journal of tissue …, 2017 - Wiley Online Library
A long‐term goal is to bioengineer, fully functional, living teeth for regenerative medicine
and dentistry applications. Biologically based replacement teeth would avoid insufficiencies …

[HTML][HTML] Enhancing the mechanical strength of 3D printed GelMA for soft tissue engineering applications

A Guo, S Zhang, R Yang, C Sui - Materials Today Bio, 2023 - Elsevier
Gelatin methacrylate (GelMA) hydrogels have gained significant traction in diverse tissue
engineering applications through the utilization of 3D printing technology. As an artificial …

Gelatin methacrylate hydrogels culture model for glioblastoma cells enriches for mesenchymal-like state and models interactions with immune cells

N Shah, PM Hallur, RA Ganesh, P Sonpatki, D Naik… - Scientific reports, 2021 - nature.com
Glioblastoma is the most lethal primary malignant brain tumor in adults. Simplified two-
dimensional (2D) cell culture and neurospheres in vitro models fail to recapitulate the …

Bioinspired microstructures through decellularization of plants for tissue engineering applications

Y Arslan, A Paradiso, N Celiktas, T Erdogan… - European Polymer …, 2023 - Elsevier
In nature, various patterns such as branches, stripes, spirals, and hexagons exist in
biological and natural systems, from nano-to macro-scale. These hierarchical structures …