[HTML][HTML] Amyloid-beta peptide and tau protein crosstalk in Alzheimer's disease

AR Roda, G Serra-Mir, L Montoliu-Gaya… - Neural regeneration …, 2022 - journals.lww.com
Alzheimer's disease is a neurodegenerative disease that accounts for most of the 50-million
dementia cases worldwide in 2018. A large amount of evidence supports the amyloid …

[HTML][HTML] Neuroinflammation in Alzheimer's disease

IG Onyango, GV Jauregui, M Čarná, JP Bennett Jr… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

[HTML][HTML] Sexual dimorphism in the 3xTg-AD mouse model and its impact on pre-clinical research

JL Dennison, NR Ricciardi, I Lohse… - Journal of …, 2021 - content.iospress.com
Female sex is a leading risk factor for developing Alzheimer's disease (AD). Sexual
dimorphism in AD is gaining attention as clinical data show that women are not only more …

[HTML][HTML] Aducanumab and its effects on tau pathology: is this the turning point of amyloid hypothesis?

S Silvestro, A Valeri, E Mazzon - International Journal of Molecular …, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions of people
around the world. The two main pathological mechanisms underlying the disease are beta …

Engineering of structural and functional properties of nanotherapeutics and nanodiagnostics for intranasal brain targeting in Alzheimer's

NS Hinge, H Kathuria, MM Pandey - Applied Materials Today, 2022 - Elsevier
Alzheimer's disease (AD) is the fifth leading cause of death on the planet. It hallmarks the
presence of amyloid plaques and neurofibrillary tangles in geriatric patients. The condition …

[HTML][HTML] Cognitive impairment in the 3xTg-AD mouse model of Alzheimer's disease is affected by Aβ-immunotherapy and cognitive stimulation

AR Roda, G Esquerda-Canals, J Martí-Clúa, S Villegas - Pharmaceutics, 2020 - mdpi.com
Clinical symptoms of Alzheimer's Disease (AD) include behavioral alterations and cognitive
impairment. These functional phenotypes early occur in triple-transgenic (3xTg-AD) mice …

Geroprotective interventions in the 3xTg mouse model of Alzheimer's disease

MM Sonsalla, DW Lamming - Geroscience, 2023 - Springer
Alzheimer's disease (AD) is an age-associated neurodegenerative disease. As the
population ages, the increasing prevalence of AD threatens massive healthcare costs in the …

[HTML][HTML] Application of antibody fragments against Aβ with emphasis on combined application with nanoparticles in Alzheimer's disease

ZT Sun, C Ma, GJ Li, XY Zheng, YT Hao… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases and
accumulating evidences suggest a key role of amyloid-β (Aβ) peptide in the pathogenesis of …

[HTML][HTML] Fermented Gastrodia elata Bl. Alleviates Cognitive Deficits by Regulating Neurotransmitters and Gut Microbiota in D-Gal/AlCl3-Induced Alzheimer's Disease …

Y Wang, M Zhao, C Xie, L Li, L Lin, Q Li, L Li, F Chen… - Foods, 2024 - mdpi.com
Alzheimer's disease (AD) is a common neurological disease with recognition ability loss
symptoms and a major contributor to dementia cases worldwide. Gastrodia elata Bl.(GE), a …

Genetic architecture of hippocampus subfields volumes in Alzheimer's disease

J Cai, W Xiong, X Wang, H Tan… - CNS Neuroscience …, 2024 - Wiley Online Library
Background The hippocampus is a heterogeneous structure, comprising histologically and
functionally distinguishable hippocampal subfields. The volume reductions in hippocampal …