The new WHO classification of adrenal cortical proliferations reflects translational advances
in the fields of endocrine pathology, oncology and molecular biology. By adopting a …

Adrenal tumors are commonly discovered incidentally on cross-sectional abdominal
imaging performed for reasons other than adrenal mass. Incidence of adrenal tumors …

Adrenal incidentalomas are adrenal masses detected on imaging performed for reasons
other than suspected adrenal disease. In most cases, adrenal incidentalomas are …

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Neuroendocrine
and Adrenal Gland Tumors focus on the diagnosis, treatment, and management of patients …

Two different primary malignancies can arise from the adrenal gland: adrenocortical
carcinoma (ACC) from the adrenal cortex and malignant phaeochromocytoma from the …

Background Cross-sectional imaging regularly results in incidental discovery of adrenal
tumours, requiring exclusion of adrenocortical carcinoma (ACC). However, differentiation is …

Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …

Background Adrenocortical carcinoma (ACC) is an extremely rare, aggressive tumor with
few effective therapeutic options or drugs. Mitotane (Mtn), which is the only authorized …

PURPOSE Adrenocortical carcinoma (ACC) is a rare aggressive pediatric malignancy with
distinct biology. Its treatment follows the principles developed for adults; pediatric-specific …

Importance Cushing syndrome is defined as a prolonged increase in plasma cortisol levels
that is not due to a physiological etiology. Although the most frequent cause of Cushing …